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Cerebral Venous Regulation

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Cerebral Venous System in Acute and Chronic Brain Injuries

Part of the book series: Springer Series in Translational Stroke Research ((SSTSR))

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Abstract

The overwhelming emphasis of the cerebrovascular regulation has been on understanding the artery system; few studies, however, have focused on the cerebral venous regulation, consequently, the modes and characteristics of cerebral venous regulation are largely unknown. Because 70–80% of the cerebral blood volume is located in the veins, the regulation of the cerebral venous system is as important as the cerebral artery system, especially in attenuating intracranial pressure, cerebral edema and hemorrhagic transformation. In this article, we will try to prove the presence of cerebral venous regulation from direct and indirect evidence. Furthermore, we analyzed the characteristics of the cerebral venous system from neurovascular coupling, cerebral autoregulation and cerebrovascular reactivity. From previous studies, we have come to the conclusion that the cerebral venous system may also have a vascular regulating function, which relates to the occurrence, development and prognosis of diseases. Like the cerebral arterial system, neurovascular coupling, cerebral autoregulation, and cerebrovascular reactivity can act as three evaluation indexes in cerebral venous regulation. The integrated cerebrovascular regulation, including cerebral arterial regulation and cerebral venous regulation, is a more reasonable method of evaluating cerebrovascular function.

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Financial Support

This study was supported by the National Key R&D Program of China (2016YFC1301600) to Yi Yang.

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Authors and Affiliations

  1. Clinical Trial and Research Center for Stroke, Department of Neurology, The First Hospital of Jilin University, Changchun, China

    Zhenni Guo & Yi Yang

  2. Departments of Anesthesiology, Physiology and Neurosurgery, School of Medicine, Loma Linda University, Loma Linda, CA, USA

    Zhenni Guo & Lu-Sha Tong

  3. Department of Neurology, The First Hospital of Jilin University, Changchun, China

    Hang Jin, Xin Sun & Yi Yang

  4. Department of Neurology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China

    Lu-Sha Tong

  5. Department of Anesthesiology and Physiology, Loma Linda University, Loma Linda, CA, USA

    John H. Zhang

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  1. Zhenni Guo
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  2. Hang Jin
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  3. Xin Sun
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  4. Lu-Sha Tong
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  5. John H. Zhang
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Editors and Affiliations

  1. Department of Neurology, The Second Affiliated Hospital of School of Medicine, Zhejiang University, Hangzhou, China

    Min Lou

  2. Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China

    Jianmin Zhang

  3. Beijing Tiantan Hospital, Capital Medical University, Beijing, China

    Yilong Wang

  4. Department of Neurosurgery Tangdu Hospital, PLA Air Force Medical University, Xian, USA

    Yan Qu

  5. Department of Neurology, Medical University of South Carolina, Charleston, SC, USA

    Wuwei Feng

  6. Xuanwu Hospital Neurosurgery, Capital Medical University, Beijing, China

    Xunming Ji

  7. Department of Anesthesiology and Physiology, Loma Linda University, Loma Linda, CA, USA

    John H. Zhang

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Guo, Z., Jin, H., Sun, X., Tong, LS., Zhang, J.H., Yang, Y. (2019). Cerebral Venous Regulation. In: Lou, M., et al. Cerebral Venous System in Acute and Chronic Brain Injuries. Springer Series in Translational Stroke Research. Springer, Cham. https://doi.org/10.1007/978-3-319-96053-1_4

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  • DOI: https://doi.org/10.1007/978-3-319-96053-1_4

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