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Late-Onset Retinal Degeneration

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1085))

Abstract

Patients with late-onset retinal degeneration (LORD) usually present with nyctalopia in the fifth or sixth decade of life. The fundus shows yellowish-white, punctate deposits, usually progressive and giving rise to scalloped areas of retinal pigment epithelium (RPE) atrophy in the mid-periphery and posterior pole (Fig. 23.1). The anterior segment shows elongated zonules with central lens insertion and transillumination defect in the iris, due to iris atrophy.

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Suggested Reading

  • Cukras C, Flamendorf J, Wong WT, Ayyagari R, Cunningham D, Sieving PA. Longitudinal structural changes in late-onset retinal degeneration. Retina. 2016;36:2348–56.

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Correspondence to Tarun Sharma .

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Tsang, S.H., Sharma, T. (2018). Late-Onset Retinal Degeneration. In: Tsang, S., Sharma, T. (eds) Atlas of Inherited Retinal Diseases. Advances in Experimental Medicine and Biology, vol 1085. Springer, Cham. https://doi.org/10.1007/978-3-319-95046-4_23

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