Abstract
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection according to the 2016 Sepsis-3 consensus statement. The diagnosis of septic shock additionally requires hypotension despite adequate fluid resuscitation and high lactate. The diagnosis of sepsis requires both a suspected infection and signs of organ dysfunction. It is a very common cause of hospitalization and death. Management strategies include (1) early adequate antimicrobials, (2) aggressive resuscitation, (3) timely source control, (4) adjunctive therapies, and (5) appropriate de-escalation of therapies once the patient has stabilized.
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Kumar, A., Tremblay, V. (2019). Sepsis and Septic Shock. In: LaRosa, J. (eds) Adult Critical Care Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-94424-1_8
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DOI: https://doi.org/10.1007/978-3-319-94424-1_8
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