Skip to main content

Brain Death

  • Chapter
  • First Online:
Book cover Adult Critical Care Medicine

Abstract

Brain death is a concept that was created by an ad hoc committee of the Harvard Medical School 50 years ago. It has become an accepted standard, along with cardiopulmonary criteria, to determine death. Many have taken this acceptance by the medical profession and society at large as vindication of the concept. In this chapter, we will evaluate the historical climate and historical figures that led to the development of brain death. A theoretical case will be presented outlining some of the difficulties developing in the fraction of patients that are declared dead using brain death criteria rather than cardiorespiratory criteria. A legal view of the inception and development of brain death will be discussed. In the end, we will question whether the dead-donor rule has, in the long run, led to more or less viable organs available for transplantation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. A definition of irreversible coma. JAMA. 1968;205(6):85–8.

    Google Scholar 

  2. Dean, C. Joseph E. Murray, transplant doctor and Nobel prize winner, dies at 93. New York Times. 2012, November 27.

    Google Scholar 

  3. Wijdicks EFM, Varelas PN, Gronseth GS, Greer DM. Evidence-based guideline update: determining brain death in adults. Neurology. 2010;74:1911–8.

    Article  Google Scholar 

  4. Leatherberry WC. Heart transplants: legal problems and the need for new legislation. Case W Res L Rev. 1968;19:1073. Available at: http://scholarlycommons.law.case.edu/caselrev/vol19/iss4/17, citing Ayd, When is a person dead? Med. Sci Apr. 1976 at 33–34; and Fletcher GP. Prolonging life. Wash L Rev. 1967;42:999, 1001.

  5. KAN. STAT. ANN. §77–202. 1970.

    Google Scholar 

  6. 121 Pa. L. Rev 87. 1972.

    Google Scholar 

  7. President’s Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research. Defining death: a report on the medical, legal and ethical issues in the determination of death. Washington, DC: Government Printing Office; 1981.

    Google Scholar 

  8. Spears v. Rosen, No. RG15760730. Ca. April 20, 2018.

    Google Scholar 

  9. Iverson KV. Dying to know: introduction. In: Iverson KV, editor. Death to dust: what happens to dead bodies? Tuscon: Galen Press, Ltd.; 1994. p. 11–49, 307–364.

    Google Scholar 

  10. McRae D. Every second counts. London: G. P. Putnam’s Sons; 2006.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to David C. Kaufman .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Shaw, M.H., Kaufman, D.C. (2019). Brain Death. In: LaRosa, J. (eds) Adult Critical Care Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-94424-1_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-94424-1_12

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-94423-4

  • Online ISBN: 978-3-319-94424-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics