The Development of an Innovative Corneal Biopsy Tool: A Usability Comparison of Four Ergonomic Handle Prototypes

Conference paper
Part of the Advances in Intelligent Systems and Computing book series (AISC, volume 779)


Keratitis, or an inflammation of the cornea, is a common eye disease in which a biopsy of the cornea is required to determine its underlying cause. Currently, no standardized tool is available for this purpose and corneal scrapings are performed with a scalpel or wide needle, frequently with inconclusive results as too little material is removed for fear of penetration. Previous research resulted in a new cutting principle, and is used in this follow-up study. The aim of this research is to optimize the usability of the cutting principle through a user evaluation (N = 18) of four ergonomic handle prototypes. The results of this study suggest that a forceps-shaped handle provides improved usability, and propose design guidelines for further optimization.


Corneal biopsy Keratitis Hand tool ergonomics 



This paper is the result of a collaborative research between the Department of Ophthalmology (UZA), Centre for Cell Therapy and Regenerative Medicine (Ophthalmology/Vaxinfectio – UA/UZA) and the Department of Product Development (UA) together with the industrial partner D.O.R.C. Additionally, we want to acknowledge all students contributing to this publication within the course of Applied Research Methods at Product Development, University of Antwerp.


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Product Development, Faculty of Design SciencesUniversity of AntwerpAntwerpBelgium
  2. 2.Department of Ophthalmology, Faculty of Medicine and Health Sciences, Visual Optics and Visual RehabilitationUniversity of AntwerpAntwerpBelgium

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