Abstract
Drugs are aimed at the prevention or treatment of diseases, but their positive effect cannot be guaranteed in any case. The chapter describes a few clinical cases of diseases contracted by the patient from particulate contaminants contained as foreign bodies in the drug either as such or in the form of their precursors. The cases were studied analysing the biopsic pathological samples by means of a scanning electron microscope coupled with an X-ray microprobe of an energy dispersive system. Once the foreign bodies are identified, an anamnestic work is performed to trace them in the patient’s environment and lifestyle, including the drugs he/she takes.
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EU Project:Nanopathology FP4-QOL-2002-147
EU Project: DIPNA-FP5-NMP-2006-9-03231
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© 2018 American Association of Pharmaceutical Scientists
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Gatti, A.M., Montanari, S. (2018). The Side Effects of Drugs: Nanopathological Hazards and Risks. In: Merkus, H., Meesters, G., Oostra, W. (eds) Particles and Nanoparticles in Pharmaceutical Products. AAPS Advances in the Pharmaceutical Sciences Series, vol 29. Springer, Cham. https://doi.org/10.1007/978-3-319-94174-5_13
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DOI: https://doi.org/10.1007/978-3-319-94174-5_13
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