Dengue: A Silent Killer, a Worldwide Threat
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Nowadays, the timely and effective management of mosquito-borne diseases is a crucial public health challenge to deal with. Dengue is an emerging mosquito-borne infectious disease transmitted by Aedes species. Around 3.9 billion people from more than 128 countries were affected by dengue fever. Recent research outlined that dengue can damage the platelet, disrupting the endothelium bed and provoking immune responses, resulting in severe illness. The illness extends to other vital organs, resulting in homeostasis imbalance. Currently, no vaccines, drugs, or vector control measures showed full efficacy to prevent or manage this arbovirus threat. The present chapter discussed our knowledge about dengue basic biology, epidemiology, clinical aspects, and vector control measures. In the final section, several issues to be addressed by further research are critically analyzed.
KeywordsAedes aegypti Aedes albopictus Arbovirus Culicidae Epidemiology Invasive mosquito species Pesticides Vaccine
This work was supported by the Putra Grant, Universiti Putra Malaysia, Malaysia (9470200); the authors would like to extend their sincere appreciation to the Deanship of Scientific Research at King Saud University for its funding of this research through the Research Group Project No. RG-1435-065.
Conflict of Interest: The authors declare that there is no conflict of interest regarding the publication of this study.
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