Skip to main content
SpringerLink
Log in

Promising New Treatments for Chronic Pain

  • Chapter
  • First Online:
Sciatica and Chronic Pain

Abstract

There is general agreement among researchers, clinicians and patients that we need better treatments for chronic neuropathic pain. With the rapid advances in our understanding of genetics and molecular biology in the last 25 years there is renewed enthusiasm that better treatments can be developed. Considering the complexity of pain transmission at the molecular level described earlier in this book, not surprisingly, there are a large number of potential targets for the development of new drugs. It is not the goal of this chapter to provide a complete list of potential new drugs for treating chronic pain but rather to provide examples of the process of new drug development and of several promising new drugs.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 29.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 39.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 39.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Suggested Additional Reading

  • Bornini S, Rase G. Editorial: first in-human trials – what we can learn from tragic failures. N Engl J Med. 2016;375:1786–9.

    Google Scholar 

  • Crile GW. The kinetic theory of shock and its prevention through anoci-association (shockless operation). Lancet. 1913;182:7–16.

    Article  Google Scholar 

  • Lane NE, Schnitzer TJ, Birbara CA, et al. Tanezumab for treatment of pain from osteoarthritis of the knee. N Engl J Med. 2010;363:1521–31.

    Article  CAS  PubMed  Google Scholar 

  • Manglik A, Lin H, Aryal DK, et al. Structure-based discovery of opioid analgesics with reduced side effects. Nature. 2016;537:185–90.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rahn EJ, Hohmann AG. Cannabinoids as pharmacotherapies for neuropathic pain: from the bench to the bedside. Neurotherapeeutics. 2009;6:713–37.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neurology, University of California, Los Angeles, Los Angeles, CA, USA

    Robert W. Baloh MD

Authors
  1. Robert W. Baloh MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Baloh, R.W. (2019). Promising New Treatments for Chronic Pain. In: Sciatica and Chronic Pain. Springer, Cham. https://doi.org/10.1007/978-3-319-93904-9_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-93904-9_9

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-93903-2

  • Online ISBN: 978-3-319-93904-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation