Abstract
This chapter reviews the fundamentals in acid-base interpretation and the differential diagnosis for each acid-base pattern. We also discuss oxygen transfer physiology and pathophysiology with a final case based illustration of the topic.
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References
Bear RA, Dyck RF. Clinical approach to the diagnosis of acid-base disorders. Can Med Assoc J. 1979;120:173–82.
Kassirer J, Bleich H. Rapid estimation of plasma carbon dioxide tension from pH and total carbon dioxide content. N Engl J Med. 1965;272:1067.
Emmett M, Narins RG. Clinical use of the anion gap. Medicine (Baltimore). 1977;56:38–54.
Lennon E, Lemann JJ. Defense of hydrogen ion concentration in chronic metabolic acidosis. A new evaluation of an old approach. Ann Intern Med. 1966;65:265.
Narins RG, Emmett M. Simple and mixed acid-base disorders: a practical approach. Medicine (Baltimore). 1980;59:161–87.
Albert MS, Dell RB, Winters RW. Quantitative displacement of acid-base equilibrium in metabolic acidosis. Ann Intern Med. 1967;66:312–22.
Dubose TD. Acid–base disorders. In: Brenner BM, editor. Brenner and Rector’s The Kidney. 6th ed. Philadelphia, PA: WB Saunders; 2000. p. 925–97.
Batlle DC, Hizon M, Cohen E, Gutterman C, Gupta R. The use of the urinary anion gap in the diagnosis of hyperchloremic metabolic acidosis. N Engl J Med. 1988;318:594–9.
Oliva P. Severe alveolar hypoventilation in a patient with metabolic alkalosis. Am J Med. 1972;52:817.
Cuomo A, Lifshitz M, Brasch R, Al E. Marked hypercapnia secondary to severe metabolic alkalosis. Ann Intern Med. 1972;177:405.
Javaheri S, Kazemi H. Metabolic alkalosis and hypoventilation in humans. Am Rev Respir Dis. 1987;136:1011–6.
Fulop M. Hypercapnia in metabolic alkalosis. NY State J Med. 1976;76:19.
de Strihou VY, Frans A. The respiratory response to chronic metabolic alkalosis and acidosis in disease. Clin Sci Mol Med. 1973;45:439–48.
NCJ B, Cohen JJ, Schwartz WB. Carbon dioxide titration curve of normal man. Effect of increasing degrees of acute hypercapnia on acid-base equilibrium. N Engl J Med. 1965;272:6–12.
Schwartz WB, NCJ B, Cohen JJ. The response of extracellular hydrogen ion concentration to graded degrees of chronic hypercapnia: the physiologic limits of the defense of pH. J Clin Invest. 1965;44:291–301.
Arbus GS, Herbert LA, Levesque PR, Etsten BE, Schwartz WB. Characterization and clinical application of the “significance band” for acute respiratory alkalosis. N Engl J Med. 1969;280:117–23.
Gennari FJ, Goldstein MB, Schwartz WB. The nature of the renal adaptation to chronic hypocapnia. J Clin Invest. 1972;51:1722–30.
Weil JV. Ventilatory control at high altitude. In: Fishman AP, editor. Handbook of physiology. Section 3: the respiratory system. Bethesda, MD: American Physiological Society; 1986. p. 703–27.
Goldberg M, Green SB, Moss ML, et al. Computer-based instruction and diagnosis of acid-base disorders: a systematic approach. JAMA. 1973;223:266–75.
Mellemgaard K. The alveolar-arterial oxygen difference: its size and components in normal man. Acta Physiol Scand. 1966;67:10–20.
West JB. Respiratory physiology: the essentials. Philadelphia, PA: Lippincott Williams & Wilkins; 2012.
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Altalag, A., Road, J., Wilcox, P., Aboulhosn, K. (2019). Arterial Blood Gas (ABG) Interpretation. In: Altalag, A., Road, J., Wilcox, P., Aboulhosn, K. (eds) Pulmonary Function Tests in Clinical Practice. In Clinical Practice. Springer, Cham. https://doi.org/10.1007/978-3-319-93650-5_8
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