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Hematologic Challenges in the Critically Ill pp 259–278Cite as

Hematologic Challenges in Intensive Care Unit Patients with Solid Organ Transplants

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Abstract

Solid organ transplant recipients represent a select population exposed to immunosuppression, antibiotics, opportunistic infections, and surgical trauma. Many of these patients will require intensive care unit management; here we present the most common hematologic challenges. “Closed” intensive care units are the current trend in the United States, with the intensivist functioning as the primary physician and remaining teams functioning as consultants. Most intensivists have had very little exposure to transplant patients; therefore, it is important to be familiar with common hematologic conditions and associated treatment algorithms affecting the transplant population. The first section reviews specific hematologic challenges in liver and kidney transplant recipients, which are the most common solid organ transplants. In the subsequent section, we will review opportunistic infections, immunosuppressants, and antimicrobials that have a hematologic impact in the solid organ transplant population. The last section will focus on miscellaneous hematologic conditions in the transplant population, including graft-versus-host disease and post-transplant lymphoproliferative disease.

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Authors and Affiliations

  1. Department of Surgery, Division of Transplant Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA

    Gerardo Tamayo-Enríquez & Daniel Borja-Cacho

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  1. Gerardo Tamayo-Enríquez
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  2. Daniel Borja-Cacho
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Correspondence to Gerardo Tamayo-Enríquez .

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Editors and Affiliations

  1. Department of Anesthesiology, Critical Care and Hyperbaric Medicine, Team Health Research Institute, Englewood, NJ, USA

    Aryeh Shander

  2. Department of Critical Care Medicine, Geisinger Health System, Danville, PA, USA

    Howard L. Corwin

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Tamayo-Enríquez, G., Borja-Cacho, D. (2018). Hematologic Challenges in Intensive Care Unit Patients with Solid Organ Transplants. In: Shander, A., Corwin, H. (eds) Hematologic Challenges in the Critically Ill. Springer, Cham. https://doi.org/10.1007/978-3-319-93572-0_14

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  • DOI: https://doi.org/10.1007/978-3-319-93572-0_14

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