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Targeted Ablative Therapies for Prostate Cancer

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Genitourinary Cancers

Part of the book series: Cancer Treatment and Research ((CTAR,volume 175))

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Abstract

Men diagnosed with low- to intermediate-risk, clinically localized prostate cancer (PCa) often face a daunting and difficult decision with respect to treatment: active surveillance (AS) or radical therapy. This decision is further confounded by the fact that many of these men diagnosed, by an elevated PSA, will have indolent disease and never require intervention. Radical treatments, including radical prostatectomy and whole-gland radiation, offer greater certainty for cancer control, but at the risk of significant urinary and/or sexual morbidity. Conversely, AS preserves genitourinary function and quality of life in exchange for burdensome surveillance and the psychological impact of living with cancer.

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Authors and Affiliations

  1. Department of Urology, Icahn School of Medicine at Mount Sinai, New York, USA

    Jared S. Winoker, Harry Anastos & Ardeshir R. Rastinehad

  2. Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, USA

    Ardeshir R. Rastinehad

Authors
  1. Jared S. Winoker
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  2. Harry Anastos
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  3. Ardeshir R. Rastinehad
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Correspondence to Ardeshir R. Rastinehad .

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Editors and Affiliations

  1. Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA

    Siamak Daneshmand

  2. City of Hope National Medical Center, Duarte, CA, USA

    Kevin G. Chan

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Winoker, J.S., Anastos, H., Rastinehad, A.R. (2018). Targeted Ablative Therapies for Prostate Cancer. In: Daneshmand, S., Chan, K. (eds) Genitourinary Cancers . Cancer Treatment and Research, vol 175. Springer, Cham. https://doi.org/10.1007/978-3-319-93339-9_2

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