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Outcomes of Different Antihypertensive Regimens

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Abstract

In this review, we introduce the main results of nine historical and landmark clinical trials, TOMHS, INSIGHT, LIFE, ALLHAT, ANBP2, CONVINCE, VALUE, ASCOT-CAFE, and ACCOMPLISH, that had a major impact on current guidelines for the management of hypertension. The most important objectives in the management of hypertension are to reduce BP levels significantly in the early phase and to reach the BP goals without fail, especially in high-risk patients with hypertensive complications. We must make every effort to confer the benefits of antihypertensive therapy to hypertensive patients, in order to reduce their cardiovascular outcomes and extend their healthy life spans.

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Author information

Authors and Affiliations

  1. Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan

    Takeshi Fujiwara

  2. Higashiagatsuma-machi National Health Insurance Clinic, Gunma, Japan

    Takeshi Fujiwara

  3. Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan

    Kazuomi Kario

Authors
  1. Takeshi Fujiwara
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  2. Kazuomi Kario
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Correspondence to Kazuomi Kario .

Editor information

Editors and Affiliations

  1. Georgetown University and VA Medical Center, Washington, DC, USA

    Vasilios Papademetriou

  2. Fourth Internal Medicine Department, Evangelismos State General Hospital, Athens, Greece

    Emmanuel A. Andreadis

  3. Fourth Internal Medicine Department, Evangelismos State General Hospital, Athens, Greece

    Charalampia Geladari

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Fujiwara, T., Kario, K. (2019). Outcomes of Different Antihypertensive Regimens. In: Papademetriou, V., Andreadis, E., Geladari, C. (eds) Management of Hypertension. Springer, Cham. https://doi.org/10.1007/978-3-319-92946-0_11

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  • DOI: https://doi.org/10.1007/978-3-319-92946-0_11

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-92945-3

  • Online ISBN: 978-3-319-92946-0

  • eBook Packages: MedicineMedicine (R0)

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