Abstract
This chapter is about the genes and mutations that underlie syndromes associated with an inherited predisposition to develop gastrointestinal (GI) tumors and cancer. Because of this focus on genes and inheritance it does not restrict its comments to the management of a patient with cancer, but focuses on a different unit of careāthe family.
While reading this chapter it is essential to remember that our knowledge of genetics, cancer and links between genes and cancer will change over time. This changing knowledge means the information in this chapter will become out of date. A number of online resources are listed at the end of the chapter and they should be consulted for up-to-date information.
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Recommended Reading
Family History
Lu KH, et al. American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers. J Clin Oncol. 2014;32:833ā41.
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Poplawski, N.K. (2019). Genetics of Inherited Gastrointestinal Tumors. In: Wichmann, M., McCullough, T., Roberts-Thomson, I., Maddern, G. (eds) Gastroenterology For General Surgeons. Springer, Cham. https://doi.org/10.1007/978-3-319-92768-8_21
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DOI: https://doi.org/10.1007/978-3-319-92768-8_21
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