Skip to main content

Bayesian Statistics: Markov Chain Monte Carlo Sampling

  • Chapter
  • First Online:
Modern Bayesian Statistics in Clinical Research

Abstract

Markov chain Monte Carlo (MCMC) procedures can be laid out as Bayesian tests. The Bayesian prior likelihood distribution of MCMC procedures could, for example, be a data file with missing data. The posterior likelihood distribution is based on the prior plus the MCMC computed imputation values. In a 500 patient multiple variables model with missing data five MCMC imputated models were produced with the help of the multiple imputations module in SPSS statistical software. The correlation coefficients of the predictor versus outcome values in the original data and those of five MCMC imputated models were respectively

  • 0.533

  • 0.596

  • 0.567

  • 0.594

  • 0.586

  • 0.580.

The Bayes factors of the Bayesian analyses of the above imputated models were respectively

  • 1.187963

  • 2.671638

  • 1.518048

  • 2.537739

  • 2.142738

  • 1.90718.

We conclude that both the traditional correlation coefficients of the imputated models and their Bayes factors were consistently robuster. However, the magnitudes of the Bayes factors increased over 100%, while the magnitudes of the traditional correlation coefficients increased by 8% at best.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 99.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    To readers requesting more background, theoretical and mathematical information of computations given, several textbooks complementary to the current production and written by the same authors are available.

  2. 2.

    All of them have been written by the same authors, and they have been edited by Springer Heidelberg Germany.

Suggested Reading ,

To readers requesting more background, theoretical and mathematical information of computations given, several textbooks complementary to the current production and written by the same authors are available.

All of them have been written by the same authors, and they have been edited by Springer Heidelberg Germany.

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Cleophas, T.J., Zwinderman, A.H. (2018). Bayesian Statistics: Markov Chain Monte Carlo Sampling. In: Modern Bayesian Statistics in Clinical Research . Springer, Cham. https://doi.org/10.1007/978-3-319-92747-3_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-92747-3_12

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-92746-6

  • Online ISBN: 978-3-319-92747-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics