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Potential Clinical Advantages of Drug-Coated Balloon in Specific Clinical Settings

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Drug-Coated Balloons

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Abstract

New generation drug-eluting stents (DES) have shown excellent results regarding rates of in-stent restenosis. Nevertheless limitations of DES still exist and include concerns about stent thrombosis, increased bleeding risk due to prolonged dual antiplatelet therapy, and limited access for future coronary bypass grafting. Not only these limitations, but also the increase of complex percutaneous coronary interventions as well as the establishment of hybrid revascularization strategies have led to the development of drug coated balloons (DCB). These interventional devices provide mechanical expansion to a coronary stenosis and deliver antiproliferative drugs without leaving permanent metal scaffolds behind. While there is already robust evidence for an indication of DCB angioplasty in the treatment of metallic in-stent restenosis, further clinical scenarios have been investigated for the use of DCB with promising results for some of them. Current data on clinical scenarios with potential advantages of DCB angioplasty are summarized in this chapter.

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Authors and Affiliations

  1. Interventional Cardiovascular Research and Clinical Trials, Icahn School of Medicine at Mount Sinai, The Zena and Michael A. Wiener Cardiovascular Institute, New York, NY, USA

    Serdar Farhan, Birgit Vogel & Roxana Mehran

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  1. Serdar Farhan
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  2. Birgit Vogel
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  3. Roxana Mehran
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Correspondence to Roxana Mehran .

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Editors and Affiliations

  1. Cardiac Department, San Carlo Clinic, Milano, Italy

    Bernardo Cortese

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Farhan, S., Vogel, B., Mehran, R. (2019). Potential Clinical Advantages of Drug-Coated Balloon in Specific Clinical Settings. In: Cortese, B. (eds) Drug-Coated Balloons . Springer, Cham. https://doi.org/10.1007/978-3-319-92600-1_8

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  • DOI: https://doi.org/10.1007/978-3-319-92600-1_8

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  • Online ISBN: 978-3-319-92600-1

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