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Multifunctional Magnetic Nanocomposites on the Base of Magnetite and Hydroxyapatite for Oncology Applications

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Book cover Nanochemistry, Biotechnology, Nanomaterials, and Their Applications (NANO 2017)

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Abstract

A survey of studies carried out at the Chuiko Institute of Surface Chemistry NAS of Ukraine aimed at developing the concept of creating magnetosensitive nanocomposites (NK) with multilevel hierarchical nanoscale architecture and functions of biomedical nanorobots. The data on the synthesis of magnetically sensitive nanocomposites of core-shell type on the basis of single-domain magnetite and hydroxyapatite, the study of their magnetic properties, features of immobilization on the surface of oncological preparations of different action mechanisms, bioactivity testing, creation of magnetic fluids on the basis of synthesized NK, and the establishment of the prospects of their use in oncology are presented.

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Acknowledgments

The work was carried out with the support of the target comprehensive program of fundamental research of the National Academy of Sciences of Ukraine “Fundamental problems of the creation of new nanomaterials and nanotechnologies” for 2015–2019 (Project No. 38/17-n). The publication contains the results of research conducted with the grant support of the State Fund for Fundamental Research (project 31566).

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Pylypchuk, I.V. et al. (2018). Multifunctional Magnetic Nanocomposites on the Base of Magnetite and Hydroxyapatite for Oncology Applications. In: Fesenko, O., Yatsenko, L. (eds) Nanochemistry, Biotechnology, Nanomaterials, and Their Applications. NANO 2017. Springer Proceedings in Physics, vol 214. Springer, Cham. https://doi.org/10.1007/978-3-319-92567-7_2

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