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Numerical Analysis of Natural Outbreaks and Intentional Releases of Emerging and Re-emerging Pathogens: Preliminary Evidence

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Enhancing CBRNE Safety & Security: Proceedings of the SICC 2017 Conference

Abstract

The outbreaks of emerging and re-emerging infectious diseases (related to natural, accidental, or intentional releases of pathogens) are a major concern for CBRNe experts. The aim of this work is to test two innovative approaches to simulate: (a) the natural diffusion of an outbreak of measles using the Spatiotemporal Epidemiological Modeler (STEM) software and (b) the intentional release of anthrax spores in confined environments using the computational fluid dynamics (CFD) COMSOL Multiphysics® Modeling Software. The two approaches were compared in order to verify their consistency with the scenarios for further analysis; the preliminary evidence from this work will be applied to the development of an interdisciplinary master’s thesis in medical biotechnology based on the merging of medicine, biology, and engineering.

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References

  1. Jones, K.E., Patel, N.G., Levy, M.A., Storeygard, A., Balk, D., Gittleman, J.L., Daszak, P.: Global trends in emerging infectious diseases. Nature. 451(7181), 990–993 (2008)

    Article  ADS  Google Scholar 

  2. World Health Organization: http://www.who.int/mediacentre/factsheets/fs310/en/

  3. Fauci, A.S.: Emerging and re-emerging infectious diseases: influenza as a prototype of the host-pathogen balancing act. Cell. 124(4), 665–670 (2006)

    Article  Google Scholar 

  4. Morens, D.M., Folkers, G.K., Fauci, A.S.: The challenge of emerging and re-emerging infectious diseases. Nature. 430(6996), 242 (2004)

    Article  ADS  Google Scholar 

  5. Jansen, H.J., Breeveld, F.J., Stijnis, C., Grobusch, M.P.: Biological warfare, bioterrorism, and biocrime. Clin. Microbiol. Infect. 20(6), 488–496 (2014)

    Article  Google Scholar 

  6. Riedel, S.: Biological warfare and bioterrorism: a historical review. Proceedings (Baylor University. Medical Center). 17(4), 400 (2004)

    Article  Google Scholar 

  7. Frischknecht, F.: The history of biological warfare. EMBO Rep. 4(6S), S47–S52 (2003)

    Article  Google Scholar 

  8. Thavaselvam, D., Vijayaraghavan, R.: Biological warfare agents. J. Pharm. Bioallied Sci. 2(3), 179 (2010)

    Article  Google Scholar 

  9. Eneh, O.C.: Biological weapons-agents for life and environmental destruction. Res. J. Environ. Toxicol. 6(3), 65 (2012)

    Article  Google Scholar 

  10. World Health Organization: http://www.who.int/mediacentre/factsheets/fs286/en/

  11. Center for Diseases Control and Prevention: https://www.cdc.gov/measles/about/index.html

  12. Center for Diseases Control and Prevention: https://www.cdc.gov/anthrax/index.html

  13. Cenciarelli, O., Rea, S., Carestia, M., D’Amico, F., Malizia, A., Bellecci, C., Gaudio, P., Gucciardino, A., Fiorito, R.: Bioweapons and bioterrorism: a review of history and biological agents. Def. S&T Tech. Bull. 6(2), 111–129 (2013)

    Google Scholar 

  14. Eclipse: https://www.eclipse.org/stem/intro.php

  15. Baldassi, F., D’Amico, F., Carestia, M., Cenciarelli, O., Mancinelli, S., Gilardi, F., Malizia, A., Di Giovanni, D., Soave, P.M., Bellecci, C., Gaudio, P., Palombi, L.: Testing the accuracy ratio of the Spatio-Temporal Epidemiological Modeler (STEM) through Ebola haemorrhagic fever outbreaks. Epidemiol. Infect. 144(7), 1463–1472 (2016)

    Article  Google Scholar 

  16. Ciparisse, J.-F., Cenciarelli, O., Mancinelli, S., Ludovici, G.M., Malizia, A., Carestia, M., Di Giovanni, D., Bellecci, C., Palombi, L., Gaudio, P.: A computational fluid dynamics simulation of anthrax diffusion in a subway station. Int. J. Math. Models Methods Appl. Sci. 10, 286–291 (2016)

    Google Scholar 

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Puleio, A. et al. (2018). Numerical Analysis of Natural Outbreaks and Intentional Releases of Emerging and Re-emerging Pathogens: Preliminary Evidence. In: Malizia, A., D'Arienzo, M. (eds) Enhancing CBRNE Safety & Security: Proceedings of the SICC 2017 Conference. Springer, Cham. https://doi.org/10.1007/978-3-319-91791-7_19

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