Skip to main content

Abstract

The term conversion disorders refers to a variety of neurological symptoms genuinely experienced by the patient but inconsistent with an underlying identifiable neurologic cause. Conversion disorders have a high prevalence among population, leading to frequent hospitalization and causing significant distress and disability in patients. In the last years, a better understanding of the possible phenotypes and underlying psychopathologic mechanisms in conversion disorders has been provided. A complete neurologic examination represents the main part of the clinical assessment in patients with conversion disorders and the main tool to differentiate them from organic neurological conditions. The diagnosis of conversion disorders is based on the demonstration of positive functional signs, together with the exclusion of signs of disease. Management of conversion disorders is difficult, and many patients are reluctant to accept their diagnosis. Neurologists, psychiatrists, psychologists, and physiotherapists need to work together in order to help the patients to understand their symptoms and to heal. The following chapter provides a detailed explanation about clinical assessment, psychopathologic mechanisms, and current treatment of conversion disorders, with the aim of helping physician in the diagnosis and differential diagnosis with organic diseases. A clinical case is also presented to supply a concrete example of how insidious can be the management of a conversion disorder.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed (DSM-V). Arlington: American Psychiatric Association; 2013.

    Book  Google Scholar 

  2. Breuer J, Freud S. Studies in hysteria; 1895.

    Google Scholar 

  3. Lehn A, Gelauff J, Hoeritzauer I, et al. Functional neurological disorders: mechanisms and treatment. J Neurol. 2016;263(3):611–20.

    Article  CAS  Google Scholar 

  4. Stone J. Functional neurological disorders: the neurological assessment as treatment. Pract Neurol. 2016;16(1):7–17.

    Article  Google Scholar 

  5. Stone J, Carson A, Duncan R, et al. Who is referred to neurology clinics? – the diagnoses made in 3781 new patients. Clin Neurol Neurosurg. 2010;112(9):747–51.

    Article  CAS  Google Scholar 

  6. Carson AJ, Brown R, David AS, et al. Functional (conversion) neurological symptoms: research since the millennium. J Neurol Neurosurg Psychiatry. 2012;83(8):842–50.

    Article  Google Scholar 

  7. Tsui P, Deptula A, Yuan DY. Conversion disorder, functional neurological symptom disorder, and chronic pain: comorbidity, assessment, and treatment. Curr Pain Headache Rep. 2017;21(6):29.

    Article  Google Scholar 

  8. Stone J, Sharpe M, Binzer M. Motor conversion symptoms and pseudoseizures: a comparison of clinical characteristics. Psychosomatics. 2004;45(6):492.

    Article  Google Scholar 

  9. Stone J, Hallett M, Carson A, Bergen D, Shakir R. Functional disorders in the neurology section of ICD-11: a landmark opportunity. Neurology. 2014;83(24):2299–301.

    Article  Google Scholar 

  10. Carson A, Stone J, Hibberd C, et al. Disability, distress and unemployment in neurology outpatients with symptoms “unexplained by organic disease”. J Neurol Neurosurg Psychiatry. 2011;82:810–3.

    Article  CAS  Google Scholar 

  11. American Psychiatric Association. Diagnostic and statistical. Manual of mental disorders. 4th ed. Text revision (DSM-IV). Washington, DC: American Psychiatric Association; 2000.

    Google Scholar 

  12. Stone J, Carson A. Functional neurologic symptoms: assessment and management. Neurol Clin 2011;29(1):1–18, vii.

    Article  Google Scholar 

  13. Drouin E, Drouin G, Péréon Y. The Babinski sign. Lancet Neurol. 2017;16(3):180.

    Article  Google Scholar 

  14. Daum C, Gheorghita F, Spatola M, et al. Interobserver agreement and validity of bedside ‘positive signs’ for functional weakness, sensory and gait disorders in conversion disorder: a pilot study. J Neurol Neurosurg Psychiatry. 2015;86(4):425–30.

    Article  Google Scholar 

  15. Stone J, Carson A, Sharpe M. Functional symptoms and signs in neurology: assessment and diagnosis. J Neurol Neurosurg Psychiatry. 2005;76(Suppl 1):i2–12.

    Article  Google Scholar 

  16. Stone J, Smyth R, Carson A, et al. La belle indifférence in conversion symptoms and hysteria: systematic review. Br J Psychiatry. 2006;188:204.

    Article  Google Scholar 

  17. Avbersek A, Sisodiya S. Does the primary literature provide support for clinical signs used to distinguish psychogenic non-epileptic seizures from epileptic seizures? J Neurol Neurosurg Psychiatry. 2010;81:719–25.

    Article  Google Scholar 

  18. Beatty S. Non-organic visual loss. Postgrad Med J. 1999;75(882):201–7.

    Article  CAS  Google Scholar 

  19. Stone J, Carson A, Sharpe M. Functional symptoms in neurology: management. J Neurol Neurosurg Psychiatry. 2005;76(Suppl I):i13–21.

    Article  Google Scholar 

  20. Boeckle M, Liegl G, Jank R, Pieh C. Neural correlates of conversion disorder: overview and meta-analysis of neuroimaging studies on motor conversion disorder. BMC Psychiatry. 2016;16(1):195.

    Article  Google Scholar 

  21. Hassa T, Sebastian A, Liepert J, Weiller C, Schmidt R, Tüscher O. Symptom-specific amygdala hyperactivity modulates motor control network in conversion disorder. NeuroImage Clin. 2017;15:143–50.

    Article  Google Scholar 

  22. Hallett M, Stone J, Carson A. Imaging studies of functional neurologic disorders. Funct Neurol Disord. 2016;139:73.

    Article  Google Scholar 

  23. Morris LS, To B, Baek K, et al. Disrupted avoidance learning in functional neurological disorder: implications for harm avoidance theories. NeuroImage Clin. 2017;16:286–94.

    Article  Google Scholar 

  24. Aybek S, Nicholson TR, Zelaya F, et al. Neural correlates of recall of life events in conversion disorder. JAMA Psychiat. 2014;71(1):52–60.

    Article  Google Scholar 

  25. Scott RL, Anson JG. Neural correlates of motor conversion disorder. Mot Control. 2009;13(2):161–84.

    Article  Google Scholar 

  26. Harvey SB, Stanton BR, David AS. Conversion disorder: towards a neurobiological understanding. Neuropsychiatr Dis Treat. 2006;2(1):13–20.

    PubMed  PubMed Central  Google Scholar 

  27. Stone J, Edwards M. Trick or treat? Showing patients with functional (psychogenic) motor symptoms their physical signs. Neurology. 2012;79(3):282–4.

    Article  Google Scholar 

  28. Stone J. Functional neurological symptoms. J R Coll Physicians Edinb. 2011;41(1):38–41.

    Article  CAS  Google Scholar 

  29. Nielsen G, Stone J, Edwards MJ. Physiotherapy for functional (psychogenic) motor symptoms: a systematic review. J Psychosom Res. 2013;75:93–102.

    Article  Google Scholar 

  30. Goldstein LH, Chalder T, Chigwedere C, et al. Cognitive-behavioral therapy for psychogenic nonepileptic seizures: a pilot RCT. Neurology. 2010;74(24):1986–94.

    Article  CAS  Google Scholar 

  31. Moene FC, Spinhoven P, Hoogduin KA, et al. A randomized controlled clinical trial on the additional effect of hypnosis in a comprehensive treatment program for in-patients with conversion disorder of the motor type. Psychother Psychosom. 2002;71:66–76.

    Article  Google Scholar 

  32. Masuda D, Hayaski Y. A case of dissociative (conversion) disorder treated effectively with haloperidol: an adolescent boy who stopped talking. Seishin Igaku (Clin Psychiatry). 2003;45:663–5.

    Google Scholar 

  33. Cybulska EM. Globus hystericus – a somatic symptom of depression? The role of electroconvulsive therapy and antidepressants. Psychosom Med. 1997;59(1):67–9.

    Article  CAS  Google Scholar 

  34. Pennington C, Newson M, Hayre A, Coulthard E. Functional cognitive disorder: what is it and what to do about it? Pract Neurol. 2015;0:1–9.

    Google Scholar 

  35. Delis DC, Wetter SR. Cogniform disorder and cogniform condition: proposed diagnoses for excessive cognitive symptoms. Arch Clin Neuropsychol. 2007;22:589–604.

    Article  Google Scholar 

  36. Stone J, Pal S, Blackburn D, Reuber M, Thekkumpurath P, Carson A. Functional (psychogenic) cognitive disorders: a perspective from the neurology clinic. J Alzheimer’s Dis. 2015;48:S5–S17.

    Article  Google Scholar 

  37. Mendez MF. Non-neurogenic language disorders: a preliminary classification. Psychosomatics. 2018;59(1):28–35.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Andrea Arighi .

Editor information

Editors and Affiliations

Self-Assessment Questionnaire

Self-Assessment Questionnaire

  1. 1.

    In DSM-V and ICD-11 classifications, conversion disorders are considered:

    1. (A)

      A field of psychiatry

    2. (B)

      A field of neurology

    3. (C)

      A field in which both neurology and psychiatry are equally important

    4. (D)

      A field of psychology

  2. 2.

    The most common phenotype of conversion disorders is:

    1. (A)

      Swallowing alteration

    2. (B)

      Non-epileptic seizure

    3. (C)

      Complete blindness

    4. (D)

      Word-finding difficulty

  3. 3.

    In Daum’s proposed classification of clinical positive signs in conversion disorders, Hoover’s sign is considered:

    1. (A)

      Highly reliable

    2. (B)

      Reliable

    3. (C)

      Suggestive

    4. (D)

      Not suggestive

  4. 4.

    Poor activation at electromyography can’t be:

    1. (A)

      Related to pain

    2. (B)

      Related to poor cooperation possibly due to a functional disorder

    3. (C)

      Related to upper motor neuron lesion

    4. (D)

      A normal finding

  5. 5.

    The best therapeutic approach to functional symptoms is:

    1. (A)

      Antidepressants

    2. (B)

      Neuroleptics

    3. (C)

      Electroconvulsive therapy

    4. (D)

      A good explanation to the patient of the nature of his functional symptoms and the sharing of physical signs

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Carandini, T., Arighi, A., Scarpini, E. (2019). Conversion Disorders Across Psychiatry and Neurology. In: Altamura, A., Brambilla, P. (eds) Clinical Cases in Psychiatry: Integrating Translational Neuroscience Approaches. Springer, Cham. https://doi.org/10.1007/978-3-319-91557-9_13

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-91557-9_13

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-91556-2

  • Online ISBN: 978-3-319-91557-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics