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Neurostimulation in the Management of Chronic Migraine

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Abstract

Chronic migraine is both a prevalent and disabling neurologic disorder with significant impact on the health-related quality of life and economic well-being of those suffering from the condition. In tertiary headache centers, the use of both pharmacological and non-pharmacological interventions is commonplace. Available pharmacologic treatments with established efficacy in multiple randomized controlled trials are few and include oral topiramate and intramuscular onabotulinumtoxinA injections per the protocol put forth by the PREEMPT studies. Patient preference, treatment response, and treatment tolerability sometimes shift the focus of management to non-pharmacologic strategies. Among these is the emerging field of neurostimulation in the management of migraine. The aim of this chapter is to review the current body of knowledge of neurostimulation techniques including occipital nerve stimulation, transcutaneous supraorbital nerve stimulation, single-pulse transcranial magnetic stimulation, repetitive-pulse transcranial magnetic stimulation, transcranial direct current stimulation, vagus nerve stimulation, and sphenopalatine ganglion stimulation as it pertains to the management of migraine.

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Shumate, D.A., Freitag, F.G. (2019). Neurostimulation in the Management of Chronic Migraine. In: Green, M., Cowan, R., Freitag, F. (eds) Chronic Headache. Springer, Cham. https://doi.org/10.1007/978-3-319-91491-6_25

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