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Peripheral Nerve Stimulation for Head and Face Pain

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Diagnosis and Management of Head and Face Pain

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Abstract

Neuromodulation has emerged as a potentially promising therapeutic modality for many headache and facial pain disorders. Electrical stimulation of a peripheral nerve (PNS) is a mode of neuromodulation that can be used to treat not only neuropathic pain that manifests in dermatomal patterns but also primary headache disorders that affect a region of maximal pain not correlating with one specific dermatome. Common PNS strategies for head and face pain include implantation of subcutaneous electrodes to various named nerves such as occipital nerve stimulation (ONS), supraorbital nerve stimulation (SONS), sphenopalatine ganglion (SPG) stimulation, and vagal nerve stimulation (VNS).

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References

  1. Wall PD, Sweet WH. Temporary abolition of pain in man. Science (New York, NY). 1967;155:108–9.

    Article  CAS  Google Scholar 

  2. Weiner RL, Reed KL. Peripheral neurostimulation for control of intractable occipital neuralgia. Neuromodulation. 1999;2:217–21.

    Article  CAS  PubMed  Google Scholar 

  3. Petersen EA, Slavin KV. Peripheral nerve/field stimulation for chronic pain. Neurosurg Clin N Am. 2014;25:789–97.

    Article  PubMed  Google Scholar 

  4. Deogaonkar M, Machado AG, Sharan A. Pain management, an issue of neurosurgery clinics of North America, E-Book. Philadelphia, PA: Elsevier; 2014.

    Google Scholar 

  5. Levy RM. Differentiating the leaves from the branches in the tree of neuromodulation: the state of peripheral nerve field stimulation. Neuromodulation. 2011;14:201–5.

    Article  PubMed  Google Scholar 

  6. Hann S, Sharan A. Dual occipital and supraorbital nerve stimulation for chronic migraine: a single-center experience, review of literature, and surgical considerations. Neurosurg Focus. 2013;35:E9.

    Article  PubMed  Google Scholar 

  7. Goadsby PJ, Bartsch T, Dodick DW. Occipital nerve stimulation for headache: mechanisms and efficacy. Headache. 2008;48:313–8.

    Article  PubMed  Google Scholar 

  8. Melzack R, Wall PD. Evolution of pain theories. Int Anesthesiol Clin. 1970;8:3–34.

    Article  CAS  PubMed  Google Scholar 

  9. Kapural L, Mekhail N, Hayek SM, Stanton-Hicks M, Malak O. Occipital nerve electrical stimulation via the midline approach and subcutaneous surgical leads for treatment of severe occipital neuralgia: a pilot study. Anesth Analg. 2005;101:171–4, table of contents.

    Article  PubMed  Google Scholar 

  10. Schwedt TJ, Dodick DW, Hentz J, Trentman TL, Zimmerman RS. Occipital nerve stimulation for chronic headache—long-term safety and efficacy. Cephalalgia. 2007;27:153–7.

    Article  CAS  PubMed  Google Scholar 

  11. Schwedt TJ, Dodick DW, Trentman TL, Zimmerman RS. Occipital nerve stimulation for chronic cluster headache and hemicrania continua: pain relief and persistence of autonomic features. Cephalalgia. 2006;26:1025–7.

    Article  CAS  PubMed  Google Scholar 

  12. Burns B, Watkins L, Goadsby PJ. Treatment of medically intractable cluster headache by occipital nerve stimulation: long-term follow-up of eight patients. Lancet (London, England). 2007;369:1099–106.

    Article  Google Scholar 

  13. Magis D, Allena M, Bolla M, De Pasqua V, Remacle JM, Schoenen J. Occipital nerve stimulation for drug-resistant chronic cluster headache: a prospective pilot study. Lancet Neurol. 2007;6:314–21.

    Article  PubMed  Google Scholar 

  14. Rodrigo-Royo MD, Azcona JM, Quero J, Lorente MC, Acin P, Azcona J. Peripheral neurostimulation in the management of cervicogenic headache: four case reports. Neuromodulation. 2005;8:241–8.

    Article  PubMed  Google Scholar 

  15. Melvin EA Jr, Jordan FR, Weiner RL, Primm D. Using peripheral stimulation to reduce the pain of C2-mediated occipital headaches: a preliminary report. Pain Physician. 2007;10:453–60.

    PubMed  Google Scholar 

  16. Ghaemi K, Capelle HH, Kinfe TM, Krauss JK. Occipital nerve stimulation for refractory occipital pain after occipitocervical fusion: expanding indications. Stereotact Funct Neurosurg. 2008;86:391–3.

    Article  PubMed  Google Scholar 

  17. Skaribas I, Alo K. Ultrasound imaging and occipital nerve stimulation. Neuromodulation. 2010;13:126–30.

    Article  PubMed  Google Scholar 

  18. Kinfe TM, Schu S, Quack FJ, Wille C, Vesper J. Percutaneous implanted paddle lead for spinal cord stimulation: technical considerations and long-term follow-up. Neuromodulation. 2012;15:402–7.

    Article  PubMed  Google Scholar 

  19. Hayek SM, Levy R, Deer TR, editors. Neurostimulation for the treatment of chronic pain. Philadelphia, PA: Elsevier/Saunders; 2012.

    Google Scholar 

  20. Hayek SM, Jasper JF, Deer TR, Narouze SN. Occipital neurostimulation-induced muscle spasms: implications for lead placement. Pain Physician. 2009;12:867–76.

    PubMed  Google Scholar 

  21. Falowski S, Wang D, Sabesan A, Sharan A. Occipital nerve stimulator systems: review of complications and surgical techniques. Neuromodulation. 2010;13:121–5.

    Article  PubMed  Google Scholar 

  22. Eldabe S, Buchser E, Duarte RV. Complications of spinal cord stimulation and peripheral nerve stimulation techniques: a review of the literature. Pain Med (Malden, Mass). 2016;17:325–36.

    Google Scholar 

  23. Schwedt TJ, Green AL, Dodick DW. Occipital nerve stimulation for migraine: update from recent multicenter trials. Prog Neurol Surg. 2015;29:117–26.

    PubMed  Google Scholar 

  24. Sweet JA, Mitchell LS, Narouze S, et al. Occipital nerve stimulation for the treatment of patients with medically refractory occipital neuralgia: congress of neurological surgeons systematic review and evidence-based guideline. Neurosurgery. 2015;77:332–41.

    Article  PubMed  Google Scholar 

  25. Oh MY, Ortega J, Bellotte JB, Whiting DM, Alo K. Peripheral nerve stimulation for the treatment of occipital neuralgia and transformed migraine using a c1-2-3 subcutaneous paddle style electrode: a technical report. Neuromodulation. 2004;7:103–12.

    Article  PubMed  Google Scholar 

  26. Slavin KV, Nersesyan H, Wess C. Peripheral neurostimulation for treatment of intractable occipital neuralgia. Neurosurgery. 2006;58:112–9; discussion 112–9.

    Article  PubMed  Google Scholar 

  27. Johnstone CS, Sundaraj R. Occipital nerve stimulation for the treatment of occipital neuralgia-eight case studies. Neuromodulation. 2006;9:41–7.

    Article  PubMed  Google Scholar 

  28. Magown P, Garcia R, Beauprie I, Mendez IM. Occipital nerve stimulation for intractable occipital neuralgia: an open surgical technique. Clin Neurosurg. 2009;56:119–24.

    PubMed  Google Scholar 

  29. Palmisani S, Al-Kaisy A, Arcioni R, et al. A six year retrospective review of occipital nerve stimulation practice—controversies and challenges of an emerging technique for treating refractory headache syndromes. J Headache Pain. 2013;14:67.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Abhinav K, Park ND, Prakash SK, Love-Jones S, Patel NK. Novel use of narrow paddle electrodes for occipital nerve stimulation—technical note. Neuromodulation. 2013;16:607–9.

    Article  PubMed  Google Scholar 

  31. Popeney CA, Alo KM. Peripheral neurostimulation for the treatment of chronic, disabling transformed migraine. Headache. 2003;43:369–75.

    Article  PubMed  Google Scholar 

  32. Matharu MS, Bartsch T, Ward N, Frackowiak RS, Weiner R, Goadsby PJ. Central neuromodulation in chronic migraine patients with suboccipital stimulators: a PET study. Brain. 2004;127:220–30.

    Article  PubMed  Google Scholar 

  33. Saper JR, Dodick DW, Silberstein SD, McCarville S, Sun M, Goadsby PJ. Occipital nerve stimulation for the treatment of intractable chronic migraine headache: ONSTIM feasibility study. Cephalalgia. 2011;31:271–85.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Silberstein SD, Dodick DW, Saper J, et al. Safety and efficacy of peripheral nerve stimulation of the occipital nerves for the management of chronic migraine: results from a randomized, multicenter, double-blinded, controlled study. Cephalalgia. 2012;32:1165–79.

    Article  PubMed  Google Scholar 

  35. Lipton RGP, Cady R, et al. PRISM study: occipital nerve stimulation for treatment-refractory migraine. Cephalalgia. 2009;29(Suppl. 1):S30.

    Google Scholar 

  36. Lainez M. Clinical benefits of early triptan therapy for migraine. Cephalalgia. 2004;24(Suppl 2):24–30.

    Article  PubMed  Google Scholar 

  37. Fontaine D, Christophe Sol J, Raoul S, et al. Treatment of refractory chronic cluster headache by chronic occipital nerve stimulation. Cephalalgia. 2011;31:1101–5.

    Article  PubMed  Google Scholar 

  38. Mueller O, Diener HC, Dammann P, et al. Occipital nerve stimulation for intractable chronic cluster headache or migraine: a critical analysis of direct treatment costs and complications. Cephalalgia. 2013;33:1283–91.

    Article  PubMed  Google Scholar 

  39. Goldberg SW, Nahas SJ. Supratrochlear and supraorbital nerve stimulation for chronic headache: a review. Curr Pain Headache Rep. 2015;19:26.

    Article  PubMed  Google Scholar 

  40. Yancy HM, Trentman TL, Dodick DW. The effect of occipital nerve stimulation on anterior pain in primary headache disorders. Headache. 2013;52(5):897–8.

    Google Scholar 

  41. Slavin KV, Colpan ME, Munawar N, Wess C, Nersesyan H. Trigeminal and occipital peripheral nerve stimulation for craniofacial pain: a single-institution experience and review of the literature. Neurosurg Focus. 2006;21:E5.

    Article  PubMed  Google Scholar 

  42. Narouze SN, Kapural L. Supraorbital nerve electric stimulation for the treatment of intractable chronic cluster headache: a case report. Headache. 2007;47:1100–2.

    Article  PubMed  Google Scholar 

  43. Reed KL, Black SB, Banta CJ 2nd, Will KR. Combined occipital and supraorbital neurostimulation for the treatment of chronic migraine headaches: initial experience. Cephalalgia. 2010;30:260–71.

    Article  CAS  PubMed  Google Scholar 

  44. Reed KL, Will KR, Chapman J, Richter E. Combined occipital and supraoprbital neurostimulation for chronic migraine headaches: an extended case serise (abstract). Berlin, Germany: Cephalgia; 2011. p. 98–9.

    Google Scholar 

  45. Vaisman J, Lopez E, Muraoka NK. Supraorbital and supratrochlear stimulation for trigeminal autonomic cephalalgias. Curr Pain Headache Rep. 2014;18:409.

    Article  PubMed  Google Scholar 

  46. Sluder G. The role of the sphenopalatine (or Meckle’s) ganglion in nasal headaches. N Y Med J. 1908:989–90.

    Google Scholar 

  47. Devoghel JC. Cluster headache and sphenopalatine block. Acta Anaesthesiol Belg. 1981;32:101–7.

    CAS  PubMed  Google Scholar 

  48. Kudrow L, Kudrow DB, Sandweiss JH. Rapid and sustained relief of migraine attacks with intranasal lidocaine: preliminary findings. Headache. 1995;35:79–82.

    Article  CAS  PubMed  Google Scholar 

  49. Narouze S, Kapural L, Casanova J, Mekhail N. Sphenopalatine ganglion radiofrequency ablation for the management of chronic cluster headache. Headache. 2009;49:571–7.

    Article  PubMed  Google Scholar 

  50. Tepper SJ, Rezai A, Narouze S, Steiner C, Mohajer P, Ansarinia M. Acute treatment of intractable migraine with sphenopalatine ganglion electrical stimulation. Headache. 2009;49:983–9.

    Article  PubMed  Google Scholar 

  51. Khan S, Schoenen J, Ashina M. Sphenopalatine ganglion neuromodulation in migraine: what is the rationale? Cephalalgia. 2014;34:382–91.

    Article  PubMed  Google Scholar 

  52. Assaf AT, Hillerup S, Rostgaard J, et al. Technical and surgical aspects of the sphenopalatine ganglion (SPG) microstimulator insertion procedure. Int J Oral Maxillofac Surg. 2016;45:245–54.

    Article  CAS  PubMed  Google Scholar 

  53. Ansarinia M, Rezai A, Tepper SJ, et al. Electrical stimulation of sphenopalatine ganglion for acute treatment of cluster headaches. Headache. 2010;50:1164–74.

    Article  PubMed  Google Scholar 

  54. Schoenen J, Jensen RH, Lanteri-Minet M, et al. Stimulation of the sphenopalatine ganglion (SPG) for cluster headache treatment. Pathway CH-1: a randomized, sham-controlled study. Cephalalgia. 2013;33:816–30.

    Article  PubMed  PubMed Central  Google Scholar 

  55. Kirchner A, Birklein F, Stefan H, Handwerker HO. Left vagus nerve stimulation suppresses experimentally induced pain. Neurology. 2000;55:1167–71.

    Article  CAS  PubMed  Google Scholar 

  56. Sadler RM, Purdy RA, Rahey S. Vagal nerve stimulation aborts migraine in patient with intractable epilepsy. Cephalalgia. 2002;22:482–4.

    Article  CAS  PubMed  Google Scholar 

  57. Akerman S, Simon B, Romero-Reyes M. Vagus nerve stimulation suppresses acute noxious activation of trigeminocervical neurons in animal models of primary headache. Neurobiol Dis. 2017;102:96–104.

    Article  PubMed  Google Scholar 

  58. Lenaerts ME, Oommen KJ, Couch JR, Skaggs V. Can vagus nerve stimulation help migraine? Cephalalgia. 2008;28:392–5.

    Article  CAS  PubMed  Google Scholar 

  59. Mauskop A. Vagus nerve stimulation relieves chronic refractory migraine and cluster headaches. Cephalalgia. 2005;25:82–6.

    Article  CAS  PubMed  Google Scholar 

  60. Goadsby PJ, Grosberg BM, Mauskop A, Cady R, Simmons KA. Effect of noninvasive vagus nerve stimulation on acute migraine: an open-label pilot study. Cephalalgia. 2014;34:986–93.

    Article  CAS  PubMed  Google Scholar 

  61. Nesbitt AD, Marin JC, Tompkins E, Ruttledge MH, Goadsby PJ. Initial use of a novel noninvasive vagus nerve stimulator for cluster headache treatment. Neurology. 2015;84:1249–53.

    Article  CAS  PubMed  Google Scholar 

  62. Silberstein SD, Mechtler LL, Kudrow DB, et al. Non-invasive vagus nerve stimulation for the acute treatment of cluster headache: findings from the randomized, double-blind, sham-controlled ACT1 study. Headache. 2016;56:1317–32.

    Article  PubMed  PubMed Central  Google Scholar 

  63. Silberstein SD, Calhoun AH, Lipton RB, et al. Chronic migraine headache prevention with noninvasive vagus nerve stimulation: the EVENT study. Neurology. 2016;87:529–38.

    Article  PubMed  PubMed Central  Google Scholar 

  64. Gaul C, Magis D, Liebler E, Straube A. Effects of non-invasive vagus nerve stimulation on attack frequency over time and expanded response rates in patients with chronic cluster headache: a post hoc analysis of the randomised, controlled PREVA study. J Headache Pain. 2017;18:22.

    Article  PubMed  PubMed Central  Google Scholar 

  65. Kinfe TM, Pintea B, Muhammad S, et al. Cervical non-invasive vagus nerve stimulation (nVNS) for preventive and acute treatment of episodic and chronic migraine and migraine-associated sleep disturbance: a prospective observational cohort study. J Headache Pain. 2015;16:101.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA

    Shannon W. Clark, Ashwini Sharan & Chengyuan Wu

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  1. Shannon W. Clark
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  2. Ashwini Sharan
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  3. Chengyuan Wu
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Editors and Affiliations

  1. Department of Otolaryngology-HNS, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

    James Y. Suen

  2. Department of Neurosurgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

    Erika Petersen

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Clark, S.W., Sharan, A., Wu, C. (2018). Peripheral Nerve Stimulation for Head and Face Pain. In: Suen, J., Petersen, E. (eds) Diagnosis and Management of Head and Face Pain. Springer, Cham. https://doi.org/10.1007/978-3-319-90999-8_23

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  • DOI: https://doi.org/10.1007/978-3-319-90999-8_23

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