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Basic Single Antibody Identification: How Hard Can It Be?

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Immunohematology and Transfusion Medicine

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Abstract

A 52-year-old man with a history of hypertension, type 2 diabetes mellitus, and three-vessel coronary artery disease is admitted to the hospital for a coronary artery bypass graft (CABG) surgery. An ethylenediaminetetraacetic acid (EDTA) anticoagulant sample is submitted to the blood bank for type and screen along with an order for four units of red blood cells (RBCs). No transfusion history is given.

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Reference

  1. Walker PS, Hamilton JR. Identification of antibodies to red cell antigens. In: Fung MK, Grossman BJ, Hillyer CD, Westhoff CM, editors. Technical manual. 18th ed. Bethesda: AABB; 2014. p. 398–400.

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Recommended Reading

  • Avent ND, Reid ME. The Rh blood group system: a review. Blood. 2000;95:375–87.

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  • Trudell KS. Detection and identification of antibodies. In: Harmening DM, editor. Modern blood banking and transfusion practices. 6th ed. Philadelphia: F.A. Davis; 2012. p. 216–26.

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  • Walker PS, Hamilton JR. Identification of antibodies to red cell antigens. In: Fung MK, Grossman BJ, Hillyer CD, Westhoff CM, editors. Technical manual. 18th ed. Bethesda: AABB; 2014. p. 391–421.

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Authors and Affiliations

  1. Icahn School of Medicine, Mount Sinai Health System, New York, NY, USA

    Mark T. Friedman & Jeffrey S. Jhang

  2. Department of Transfusion Medicine, National Institutes of Health Clinical Center, Bethesda, MD, USA

    Kamille A. West

  3. Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, USA

    Peyman Bizargity

  4. Department of Pathology, Children’s Hospital Colorado, Aurora, CO, USA

    Kyle Annen

Authors
  1. Mark T. Friedman
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  2. Kamille A. West
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  3. Peyman Bizargity
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  4. Kyle Annen
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  5. Jeffrey S. Jhang
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Friedman, M.T., West, K.A., Bizargity, P., Annen, K., Jhang, J.S. (2018). Basic Single Antibody Identification: How Hard Can It Be?. In: Immunohematology and Transfusion Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-90960-8_1

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  • DOI: https://doi.org/10.1007/978-3-319-90960-8_1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-90959-2

  • Online ISBN: 978-3-319-90960-8

  • eBook Packages: MedicineMedicine (R0)

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