Abstract
A range of organisms including viral, bacterial, and fungal can infect the endocardium, cardiac prosthetic devices, pericardium, and myocardium. Currently, most evidence on the use of FDG PET/CT regards its use in prosthetic cardiac components and valves. It should also be noted that echocardiography, CT, and MRI play a useful role in the investigation of potential or proven cardiac infections. A good overview of these modalities, together with helpful descriptions of the pathophysiology of cardiac infections, has been described in a recent review article [1].
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Murillo H, Restrepo CS, Marmol-Velez JA, Vargas D, Ocazionez D, Martinez-Jimenez S, et al. Infectious diseases of the heart: pathophysiology, clinical and imaging overview. Radiographics. 2016;36(4):963–83.
Harisankar CN, Mittal BR, Agrawal KL, Abrar ML, Bhattacharya A. Utility of high fat and low carbohydrate diet in suppressing myocardial FDG uptake. J Nucl Cardiol. 2011;18(5):926–36.
Williams G, Kolodny GM. Suppression of myocardial 18F-FDG uptake by preparing patients with a high-fat, low-carbohydrate diet. AJR Am J Roentgenol. 2008;190(2):W151–6.
Lum DP, Wandell S, Ko J, Coel MN. Reduction of myocardial 2-deoxy-2-[18F]fluoro-D-glucose uptake artifacts in positron emission tomography using dietary carbohydrate restriction. Mol Imaging Biol. 2002;4(3):232–7.
Scholtens AM, Verberne HJ, Budde RP, Lam MG. Additional heparin preadministration improves cardiac glucose metabolism suppression over low-carbohydrate diet alone in 18F-FDG PET imaging. J Nucl Med. 2016;57(4):568–73.
Granados U, Fuster D, Pericas JM, Llopis J, Ninot S, Quintana E, et al. Diagnostic accuracy of 18F-FDG PET/CT in infective endocarditis and implantable cardiac electronic device infection: a cross-sectional study. J Nucl Med. 2016;57(11):1726–32.
Li JS, Sexton DJ, Mick N, Nettles R, Fowler VG Jr, Ryan T, et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis. 2000;30(4):633–8.
The 2015 ESC guidelines for the management of infective endocarditis. Eur Heart J. 2015;36(44):3036–7.
Yan J, Zhang C, Niu Y, Yuan R, Zeng X, Ge X, et al. The role of 18F-FDG PET/CT in infectious endocarditis: a systematic review and meta-analysis. Int J Clin Pharmacol Ther. 2016;54(5):337–42.
Kestler M, Munoz P, Rodriguez-Creixems M, Rotger A, Jimenez-Requena F, Mari A, et al. Role of (18)F-FDG PET in patients with infectious endocarditis. J Nucl Med. 2014;55(7):1093–8.
Saby L, Laas O, Habib G, Cammilleri S, Mancini J, Tessonnier L, et al. Positron emission tomography/computed tomography for diagnosis of prosthetic valve endocarditis: increased valvular 18F-fluorodeoxyglucose uptake as a novel major criterion. J Am Coll Cardiol. 2013;61(23):2374–82.
Scarsbrook A, Barrington S. Evidence based indications for the use of PET-CT in the United Kingdom 2016. https://www.rcr.ac.uk/sites/default/files/publication/bfcr163_pet-ct.pdf.
Sarrazin JF, Philippon F, Tessier M, Guimond J, Molin F, Champagne J, et al. Usefulness of fluorine-18 positron emission tomography/computed tomography for identification of cardiovascular implantable electronic device infections. J Am Coll Cardiol. 2012;59(18):1616–25.
Ahmed FZ, James J, Cunnington C, Motwani M, Fullwood C, Hooper J, et al. Early diagnosis of cardiac implantable electronic device generator pocket infection using (1)(8)F-FDG-PET/CT. Eur Heart J Cardiovasc Imaging. 2015;16(5):521–30.
Graziosi M, Nanni C, Lorenzini M, Diemberger I, Bonfiglioli R, Pasquale F, et al. Role of (1)(8)F-FDG PET/CT in the diagnosis of infective endocarditis in patients with an implanted cardiac device: a prospective study. Eur J Nucl Med Mol Imaging. 2014;41(8):1617–23.
Adler Y, Charron P, Imazio M, Badano L, Baron-Esquivias G, Bogaert J, et al. 2015 ESC guidelines for the diagnosis and management of pericardial diseases: the Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC)Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2015;36(42):2921–64.
Dong A, Dong H, Wang Y, Cheng C, Zuo C, Lu J. (18)F-FDG PET/CT in differentiating acute tuberculous from idiopathic pericarditis: preliminary study. Clin Nucl Med. 2013;38(4):e160–5.
Erba PA, Sollini M, Lazzeri E, Mariani G. FDG-PET in cardiac infections. Semin Nucl Med. 2013;43(5):377–95.
Caforio AL, Pankuweit S, Arbustini E, Basso C, Gimeno-Blanes J, Felix SB, et al. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J. 2013;34(33):2636–48, 48a–48d.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Pencharz, D. (2018). PET and Cardiac Infections. In: Wagner, T., Basu, S. (eds) PET/CT in Infection and Inflammation . Clinicians’ Guides to Radionuclide Hybrid Imaging(). Springer, Cham. https://doi.org/10.1007/978-3-319-90412-2_8
Download citation
DOI: https://doi.org/10.1007/978-3-319-90412-2_8
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-90411-5
Online ISBN: 978-3-319-90412-2
eBook Packages: MedicineMedicine (R0)