Advertisement

PET/CT in Diagnosing and Evaluating Therapy in Vasculitis

  • Thomas WagnerEmail author
Chapter
Part of the Clinicians’ Guides to Radionuclide Hybrid Imaging book series (CGRHI)

Abstract

Ths chapter discusses the value of FDG PET/CT in large vessel vasculitis. Its role in identifying large vessel vasculitis, the role of steroids, response to treatment and other relevant imaging is discussed.

References

  1. 1.
    Treglia G, Mattoli MV, Leccisotti L, Ferraccioli G, Giordano A. Usefulness of whole-body fluorine-18-fluorodeoxyglucose positron emission tomography in patients with large-vessel vasculitis: a systematic review. Clin Rheumatol. 2011;30(10):1265–75 . Review.  https://doi.org/10.1007/s10067-011-1828-9.CrossRefPubMedGoogle Scholar
  2. 2.
    Cao Q, Chen W. FDG PET imaging of large-vessel vasculitis. PET Clin. 2012;7(2):227–32.  https://doi.org/10.1016/j.cpet.2012.01.007.CrossRefPubMedGoogle Scholar
  3. 3.
    Mavrogeni S, Dimitroulas T, Chatziioannou SN, Kitas G. The role of multimodality imaging in the evaluation of Takayasu arteritis. Semin Arthritis Rheum. 2013;42(4):401–12 . Review.  https://doi.org/10.1016/j.semarthrit.2012.07.005.CrossRefPubMedGoogle Scholar
  4. 4.
    Cheng Y, Lv N, Wang Z, Chen B, Dang A. 18-FDG-PET in assessing disease activity in Takayasu arteritis: a meta-analysis. Clin Exp Rheumatol. 2013;31(1 Suppl 75):S22–7. Epub 2013 Feb 25.PubMedGoogle Scholar
  5. 5.
    Arnaud L, Haroche J, Malek Z, Archambaud F, Gambotti L, Grimon G, Kas A, Costedoat-Chalumeau N, Cacoub P, Toledano D, Cluzel P, Piette JC, Amoura Z. Is (18)F-fluorodeoxyglucose positron emission tomography scanning a reliable way to assess disease activity in Takayasu arteritis? Arthritis Rheum. 2009;60(4):1193–200.  https://doi.org/10.1002/art.24416.CrossRefPubMedGoogle Scholar
  6. 6.
    Lee SG, Ryu JS, Kim HO, Oh JS, Kim YG, Lee CK, Yoo B. Evaluation of disease activity using F-18 FDG PET/CT in patients with Takayasu arteritis. Clin Nucl Med. 2009;34(11):749–52.  https://doi.org/10.1097/RLU.0b013e3181b7db09.
  7. 7.
    Besson FL, Parienti JJ, Bienvenu B, Prior JO, Costo S, Bouvard G, Agostini D. Diagnostic performance of 18F-fluorodeoxyglucose positron emission tomography in giant cell arteritis: a systematic review and meta-analysis. Eur J Nucl Med Mol Imaging. 2011;38(9):1764–72.  https://doi.org/10.1007/s00259-011-1830-0.CrossRefPubMedGoogle Scholar
  8. 8.
    Meller J, Strutz F, Siefker U, Scheel A, Sahlmann CO, Lehmann K, Conrad M, Vosshenrich R. Early diagnosis and follow-up of aortitis with [(18)F]FDG PET and MRI. Eur J Nucl Med Mol Imaging. 2003;30(5):730–6.CrossRefPubMedGoogle Scholar
  9. 9.
    Puppo C, Massollo M, Paparo F, Camellino D, Piccardo A, Shoushtari Zadeh Naseri M, Villavecchia G, Rollandi GA, Cimmino MA. Giant cell arteritis: a systematic review of the qualitative and semiquantitative methods to assess vasculitis with 18F-fluorodeoxyglucose positron emission tomography. Biomed Res Int. 2014;2014:574248.  https://doi.org/10.1155/2014/574248. Epub 2014 Sep 1.CrossRefPubMedPubMedCentralGoogle Scholar
  10. 10.
    Blockmans D, de Ceuninck L, Vanderschueren S, Knockaert D, Mortelmans L, Bobbaers H. Repetitive 18F-fluorodeoxyglucose positron emission tomography in giant cell arteritis: a prospective study of 35 patients. Arthritis Rheum. 2006;55(1):131–7.CrossRefPubMedGoogle Scholar
  11. 11.
    Lehmann P, Buchtala S, Achajew N, Haerle P, Ehrenstein B, Lighvani H, Fleck M, Marienhagen J. 18F-FDG PET as a diagnostic procedure in large vessel vasculitis-a controlled, blinded re-examination of routine PET scans. Clin Rheumatol. 2011;30(1):37–42.  https://doi.org/10.1007/s10067-010-1598-9.CrossRefPubMedGoogle Scholar
  12. 12.
    Besson FL, de Boysson H, Parienti JJ, Bouvard G, Bienvenu B, Agostini D. Towards an optimal semiquantitative approach in giant cell arteritis: an (18)F-FDG PET/CT case-control study. Eur J Nucl Med Mol Imaging. 2014;41(1):155–66.  https://doi.org/10.1007/s00259-013-2545-1.CrossRefPubMedGoogle Scholar
  13. 13.
    Moosig F, Czech N, Mehl C, Henze E, Zeuner RA, Kneba M, Schröder JO. Correlation between 18-fluorodeoxyglucose accumulation in large vessels and serological markers of inflammation in polymyalgia rheumatica: a quantitative PET study. Ann Rheum Dis. 2004 Jul;63(7):870–3.CrossRefPubMedPubMedCentralGoogle Scholar
  14. 14.
    Hautzel H, Sander O, Heinzel A, Schneider M, Müller HW. Assessment of large-vessel involvement in giant cell arteritis with 18F-FDG PET: introducing an ROC-analysis-based cutoff ratio. J Nucl Med. 2008;49(7):1107–13.  https://doi.org/10.2967/jnumed.108.051920. Epub 2008 Jun 13CrossRefPubMedGoogle Scholar
  15. 15.
    Fuchs M, Briel M, Daikeler T, Walker UA, Rasch H, Berg S, Ng QK, Raatz H, Jayne D, Kötter I, Blockmans D, Cid MC, Prieto-González S, Lamprecht P, Salvarani C, Karageorgaki Z, Watts R, Luqmani R, Müller-Brand J, Tyndall A, Walter MA. The impact of 18F-FDG PET on the management of patients with suspected large vessel vasculitis. Eur J Nucl Med Mol Imaging. 2012;39(2):344–53.  https://doi.org/10.1007/s00259-011-1967-x. Epub 2011 Nov 10CrossRefPubMedGoogle Scholar
  16. 16.
    Both M, Ahmadi-Simab K, Reuter M, Dourvos O, Fritzer E, Ullrich S, Gross WL, Heller M, Bähre M. MRI and FDG-PET in the assessment of inflammatory aortic arch syndrome in complicated courses of giant cell arteritis. Ann Rheum Dis. 2008;67(7):1030–3.  https://doi.org/10.1136/ard.2007.082123. Epub 2008 Jan 26CrossRefPubMedGoogle Scholar
  17. 17.
    Espígol-Frigolé G, Prieto-González S, Alba MA, Tavera-Bahillo I, García-Martínez A, Gilabert R, Hernández-Rodríguez J, Cid MC. Advances in the diagnosis of large vessel vasculitis. Rheum Dis Clin North Am. 2015;41(1):125–40, ix. Review.  https://doi.org/10.1016/j.rdc.2014.10.001.
  18. 18.
    Pipitone N, Versari A, Hunder GG, Salvarani C. Role of imaging in the diagnosis of large and medium-sized vessel vasculitis. Rheum Dis Clin North Am. 2013;39(3):593–608. Review.  https://doi.org/10.1016/j.rdc.2013.02.002.CrossRefPubMedGoogle Scholar
  19. 19.
    Balink H, Bennink RJ, van Eck-Smit BL, Verberne HJ. The role of 18F-FDG PET/CT in large-vessel vasculitis: appropriateness of current classification criteria? Biomed Res Int. 2014;2014:687608. Review.  https://doi.org/10.1155/2014/687608.CrossRefPubMedPubMedCentralGoogle Scholar
  20. 20.
    Soussan M, Abisror N, Abad S, Nunes H, Terrier B, Pop G, Eder V, Valeyre D, Sberro-Soussan R, Guillevin L, Dhote R, Fain O, Mekinian A. FDG-PET/CT in patients with ANCA-associated vasculitis: case-series and literature review. Autoimmun Rev. 2014;13(2):125–31. Review.  https://doi.org/10.1016/j.autrev.2013.09.009.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Nuclear MedicineRoyal Free London NHS Foundation TrustLondonUK

Personalised recommendations