Skip to main content
SpringerLink
Log in

Immediate Skin Contact Reactions Induced by Chemicals

  • Chapter
  • First Online:
Contact Urticaria Syndrome

Part of the book series: Updates in Clinical Dermatology ((UCD))

Abstract

An ever-expanding list of causes has been reported for immediate skin contact reactions, of which most are proteins (molecular weight 10,000 to several hundred thousand daltons), but also chemical compounds of low molecular weight (less than 1,000 Da). Low molecular weight chemical agents can be indeed responsible for immediate contact skin symptoms in the differently defined categories of contact urticaria. The most important chemicals responsible for nonimmunological and immunological contact urticaria are described in this chapter. For purposes of simplification and comprehension, these have been classified into the major families of products that include fragrances and cosmetic ingredients, biocides and preservatives, and drugs, together with other categories.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Giménez-Arnau A, Maurer M, De la Cuadra J, Maibach HI. Immediate contact skin reactions, an update of contact urticaria, contact urticaria syndrome and protein contact dermatitis-“A never ending story”. Eur J Dermatol. 2010;20:552–62.

    PubMed  Google Scholar 

  2. Ale SI, Maibach HI. Occupational contact urticaria. In: Kanerva L, Elsner P, Wahlberg JE, Maibach HI, editors. Handbook of occupational dermatology. Berlin: Springer; 2000. p. 200–16.

    Chapter  Google Scholar 

  3. Lahti A. Non-immunologic contact urticaria. Acta Dermatovener (Stockholm). 1980;60(Suppl. 91):1–49.

    Google Scholar 

  4. Kligman AM. The spectrum of contact urticaria: wheals, erythema and pruritus. Dermatologic Clin. 1990;8:57–60.

    Article  CAS  Google Scholar 

  5. Coverly J, Peters L, Whittle E, Basketter DA. Susceptibility to skin stinging, non-immunologic contact urticaria and skin irritation-is there a relationship? Contact Dermatitis. 1998;38:90–5.

    Article  PubMed  CAS  Google Scholar 

  6. Lahti A, Vaananen A, Kokkonen E-L, Hannuksela M. Acetylsalicylic acid inhibits non-immunologic contact urticaria. Contact Dermatitis. 1987;16:133–5.

    Article  PubMed  CAS  Google Scholar 

  7. Johansson J, Lahti A. Topical non-steroidal anti-inflammatory drugs inhibit non-immunological immediate contact reactions. Contact Dermatitis. 1988;19:161–5.

    Article  PubMed  CAS  Google Scholar 

  8. Wakelin SH. Contact urticaria. Clin Exp Dermatol. 2001;26:132–6.

    Article  PubMed  CAS  Google Scholar 

  9. Amaro C, Goossens A. Immunological occupational contact urticaria and contact dermatitis from proteins: a review. Contact Dermatitis. 2008;58:67–75.

    Article  PubMed  Google Scholar 

  10. Goossens A, Amaro C, Géraut C. Urticaire et dermatite de contact aux protéines en pathologie professionnelle. In:Progrès en Dermato-Allergologie. Paris: John Libbey Eurotext; 2007. p. 57–70.

    Google Scholar 

  11. Castanedo-Tardan MP, Jacob SE, Baumann LS. Contact urticaria to cosmetic and toiletry ingredients. Cosmetic Dermatol. 2008;21:339–46.

    Google Scholar 

  12. Lahti A, Basketter D. Immediate contact reactions. In: Johansen JD, Frosch PJ, Lepoittevin J-P, editors. Contact dermatitis. 5th ed. Berlin: Springer; 2011. p. 137–53.

    Google Scholar 

  13. Gleich GJ, Yunginger JW. The radioallergosorbent test: a method to measure IgE antibodies, IgG blocking antibodies, and the potency of allergy extracts. Bull N Y Acad Med. 1981;57:559–67.

    PubMed  PubMed Central  CAS  Google Scholar 

  14. Vigan M. Urticaire de contact aux cosmétiques. In:Progrès en Dermato-Allergologie. Paris: John Libbey Eurotext; 2007. p. 17–34.

    Google Scholar 

  15. Cancian M, Fortina AB, Peserico A. Contact urticaria syndrome from constituents of balsam of Peru and fragrance mix in a patient with chronic urticaria. Contact Dermatitis. 1999;41:3000.

    Article  Google Scholar 

  16. Larsen WG. Perfume dermatitis. a study of 20 patients. Arch Dermatol. 1977;113:623–7.

    Article  PubMed  CAS  Google Scholar 

  17. Frosch PJ, Pirker C, Rastogi SC, Andersen K, Bruze M, Svedman C, Goossens A, White IR, Uter W, Giménez-Arnau E, Lepoittevin J-P, Menné T, Johansen JD. Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix. Contact Dermatitis. 2005;52:207–15.

    Article  PubMed  CAS  Google Scholar 

  18. Safford RJ, Basketter DA, Allenby CF, Goodwin BFJ. Immediate contact reactions to chemicals in the fragrance mix and a study of the quenching action of eugenol. Br J Dermatol. 1990;123:595–606.

    Article  PubMed  CAS  Google Scholar 

  19. Diba VC, Statham BN. Contact urticaria from cinnamal leading to anaphylaxis. Contact Dermatitis. 2003;48:119.

    Article  PubMed  CAS  Google Scholar 

  20. Forsbeck M, Skog E. Immediate reactions to patch tests with balsam of Peru. Contact Dermatitis. 1977;3:201–5.

    Article  PubMed  CAS  Google Scholar 

  21. Hausen BM, Simatupang T, Bruhn G, Evers P, Koenig WA. Identification of new allergens constituents and proof of evidence for coniferyl benzoate in balsam of Peru. Am J Contact Dermat. 1995;6:199–208.

    Article  Google Scholar 

  22. Api AM. Only Peru Balsam extracts or distillates are used in perfumery. Contact Dermatitis. 2006;54:179.

    Article  PubMed  Google Scholar 

  23. Yamamoto A, Morita A, Tsuji T, et al. Contact urticaria from geraniol. Contact Dermatitis. 2002;46:52.

    Article  PubMed  Google Scholar 

  24. Hagvall L, Bäcktorp C, Svensson S, Nyman G, Börje A, Karlberg AT. Fragrance compound geraniol forms contact allergens on air exposure. identification and quantification of oxidation products and effect on skin sensitization. Chem Res Toxicol. 2007;20:807–14.

    Article  PubMed  CAS  Google Scholar 

  25. Kanerva L, Estlander T, Jolanki R. Dental nurse’s occupational allergic contact dermatitis from eugenol used as a restorative dental material with polymethylmethacrylate. Contact Dermatitis. 1998;38:339–40.

    Article  PubMed  CAS  Google Scholar 

  26. Praven T, Pushpalatha C, Shrenik J, Sowmya SW. An unexpected positive hypersensitive reaction to eugenol. BMJ Case Rep. 2013. https://doi.org/10.1136/bcr-2013-009464.

  27. Marzulli FN, Maibach HI. Contact allergy: predictive testing of fragrance ingredients in humans by Draize and maximization tests. J Environ Pathol Toxicol. 1980;3:243–5.

    Google Scholar 

  28. Tananka S, Royds C, Buckley D, Basketter DA, Goossens A, Bruze M, Svedman C, Menné T, Johansen JD, White IR, McFadden JP. Contact allergy to isoeugenol and its derivatives: problems with allergen substitution. Contact Dermatitis. 2004;51:288–91.

    Article  Google Scholar 

  29. Vocanson M, Valeyrie M, Rozières A, Hennino A, Floc’h F, Gard A, Nicolas JF. Lack of evidence for allergenic properties of coumarin in a fragrance allergy mouse model. Contact Dermatitis. 2007;57:361–4.

    Article  PubMed  CAS  Google Scholar 

  30. Heurung AR, Raju SI, Warshaw EM. Benzophenones. Dermatitis. 2014;25:3–10.

    Article  PubMed  CAS  Google Scholar 

  31. Emonet S, Pasche-Koo F, Perin-Minisini MJ, Hauser C. Anaphylaxis to oxybenzone, a frequent constituent of sunscreens. J Allergy Clin Immunol. 2001;107:556–7.

    Article  PubMed  CAS  Google Scholar 

  32. Yesudian PD, King CM. Severe contact urticarial and anaphylaxis from benzophenone-3 (2-hydroxy-4-methoxy benzophenone). Contact Dermatitis. 2002;46:55–6.

    Article  PubMed  CAS  Google Scholar 

  33. Maibach HI, Conant M. Contact urticarial to a corticosteroid cream: polysorbate 60. Contact Dermatitis. 1977;3:350–1.

    Article  PubMed  CAS  Google Scholar 

  34. Pérez-Pérez L, García Gavín J, Piñeiro B, Zulaica A. Biologic-induced urticarial due to polysorbate 80: usefulness of prick test. Br J Dermatol. 2011;164:1119–20.

    Article  PubMed  Google Scholar 

  35. Asarch A, Scheinmann PL. Sorbitan sesquiolate: an emerging contact allergen. Dermatitis. 2008;19:339–41.

    PubMed  Google Scholar 

  36. Hardy H, Maibach H. Contact urticarial syndrome from sorbitan sesquiolate in a corticosteroid ointment. Contact Dermatitis. 1995;32:114.

    Article  PubMed  CAS  Google Scholar 

  37. EWG’s Skin Deep® Cosmetics Database. http://www.ewg.org/skindeep.

  38. Cosmetic Ingredient Review. http://www.cir-safety.org/ingredient/propylene-glycol.

  39. Funk JO, Maibach HI. Propylene glycol dermatitis: re-evaluation of an old problem. Contact Dermatitis. 1994;31:236–41.

    Article  PubMed  CAS  Google Scholar 

  40. Andersen KE, Storrs FJ. Skin irritation caused by propylene glycols. Hautarzt. 1982;33:12–4.

    PubMed  CAS  Google Scholar 

  41. Warshaw EM, Nelsen DD, Maibach HI, Marks JG, Zug KA, et al. Positive patch test reactions to lanolin: cross-sectional data from the North American Contact Dermatitis Group, 1994 to 2006. Dermatitis. 2009;20:79–88.

    PubMed  CAS  Google Scholar 

  42. Lundov MB, Moesby L, Zachariae C, Johansen JD. Contamination versus preservation of cosmetics: a review on legislation, usage, infections, and contact allergy. Contact Dermatitis. 2009;60:70–8.

    Article  PubMed  Google Scholar 

  43. Fryklöf L-E. A note on the irritant properties of sorbic acid in ointments and creams. J Pharm Pharmacol. 1958;10:719–20.

    Article  Google Scholar 

  44. Rietschel RL. Contact urticaria from synthetic cassia oil and sorbic acid limited to the face. Contact Dermatitis. 1978;4:347–9.

    Article  PubMed  CAS  Google Scholar 

  45. Clemmensen O, Hjort N. Perioral contact urticarial from sorbic acid and benzoic acid in salad dressing. Contact Dermatitis. 1982;8:1–6.

    Article  PubMed  CAS  Google Scholar 

  46. Nair B. Final report on the safety assessment of benzyl alcohol, benzoic acid and sodium benzoate. Int J Toxicol. 2001;20:23–50.

    Article  PubMed  Google Scholar 

  47. Hannuksela M, Haahtela T. Hypersensitivity reactions to food additives. Allergy. 1987;42:561–75.

    Article  PubMed  CAS  Google Scholar 

  48. Public Health England. Formaldehyde: health effects, incident management and toxicology. 2017. https://www.gov.uk/government/publications/formaldehyde-properties-incident-management-and-toxicology.

  49. Eighth Commission Directive 86/199/EC of 26 March 1986 adapting to technical progress Annexes II, IV and VI to council directive 76/768/EC on the approximation of the laws of the member states relating to cosmetic products. Off J Eur Commun 1986; L149:38–45.

    Google Scholar 

  50. Von Krogh G, Maibach HI. Contact urticaria. In: Adam RM, editor. Occupational skin disease. New York: Grune & Stratton; 1983. p. 58–69.

    Google Scholar 

  51. Torresani C, Periti I, Beski L. Contact urticaria syndrome from formaldehyde with multiple physical urticarias. Contact Dermatitis. 1996;35:174–5.

    Article  PubMed  CAS  Google Scholar 

  52. Braun J, Zana H, Purohit A. Anaphylactic reactions to formaldehyde in root canal sealant after endodontic treatment. four cases of anaphylactic shock and three of generalized urticarial. Allergy. 2003;58:1210–4.

    Article  PubMed  CAS  Google Scholar 

  53. Ogawa M, Nishinakagawa S, Yokosawa F, Yoshida T, Endo Y. Formaldehyde-specific IgE-mediated urticaria due to formaldehyde in a room environment. Jpn J Occup Med Traumatol. 2009;57:125–9.

    Google Scholar 

  54. Kireche M, Giménez-Arnau E, Lepoittevin J-P. Preservatives in cosmetics: reactivity of allergenic formaldehyde releasers toward amino acids through breakdown products other than formaldehyde. Contact Dermatitis. 2010;63:192–202.

    Article  PubMed  CAS  Google Scholar 

  55. Schnuch A, Lessmann H, Geier J, Uter W. Contact allergy to preservatives. analysis of IVDK data 1996-2009. Br J Dermatol. 2011;164:1316–25.

    Article  PubMed  CAS  Google Scholar 

  56. Thyssen JP, Engkilde K, Lundov MD, Carlsen BC, Menné T, Johansen JD. Temporal trends of preservative allergy in Denmark (1985-2008). Contact Dermatitis. 2010;62:272–3.

    Article  Google Scholar 

  57. Gonçalo M, Goossens A. Whilst Rome burns: the epidemic of contact allergy to methylisothiazolinone. Contact Dermatitis. 2013;68:257–8.

    Article  PubMed  Google Scholar 

  58. Lundov MD, Opstrup MS, Johansen JD. Methylisothiazolinone contact allergy – a growing epidemic. Contact Dermatitis. 2013;69:271–5.

    Article  PubMed  CAS  Google Scholar 

  59. Thyssen JP, Sederberg-Olsen N, Thomsen JF, Menné T. Contact dermatitis from methylisothiazolinone in a paint factory. Contact Dermatitis. 2006;54:322–4.

    Article  PubMed  CAS  Google Scholar 

  60. García-Gavín J, Vansina S, Kerre S, Naert A, Goossens A. Methylisothiazolinone, an emerging allergen in cosmetics? Contact Dermatitis. 2010;63:96–101.

    Article  PubMed  Google Scholar 

  61. Lundov MD, Zachariae C, Menné T, Johansen JD. Airborne exposure to preservative methylisothiazolinone causes severe allergic reactions. BMJ. 2012;345:e8221.

    Article  PubMed  Google Scholar 

  62. Geier J, Lessmann H, Schnuch A, Uter W. Recent increase in allergic reactions to methylchloroisothiazolinone/methylisothiazolinone: is methylisothiazolinone the culprit? Contact Dermatitis. 2012;67:334–41.

    Article  PubMed  CAS  Google Scholar 

  63. Debeuckelaere C, Moussallieh FM, Elbayed K, Namer IJ, Berl V, Giménez-Arnau E, Lepoittevin J-P. In situ chemical behaviour of methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) in reconstructed human epidermis: a new approach to the cross-reactivity issue. Contact Dermatitis. 2016;74:159–67.

    Article  PubMed  CAS  Google Scholar 

  64. Gebhardt M, Looks A, Hipler UC. Urticaria caused by type IV sensitization to isothiazolinones. Contact Dermatitis. 1997;36:314.

    Article  PubMed  CAS  Google Scholar 

  65. Guin JD, Goodman J. Contact urticaria from benzyl alcohol presenting as intolerance to saline soaks. Contact Dermatitis. 2001;45:182–3.

    Article  PubMed  CAS  Google Scholar 

  66. Walker SL, Chalmers RJG, Beck MH. Contact urticaria due to p-chloro-m-cresol. Br J Dermatol. 2004;151:927–52.

    Article  Google Scholar 

  67. Birnie AJ, English JS. 2-Phenoxyethanol-induced contact urticaria. Contact Dermatitis. 2006;54:349.

    Article  PubMed  Google Scholar 

  68. Co-Minh HB, Demoly P, Guillot B, Raison-Peyron N. Anaphylactic shock after oral intake and contact urticaria due to polyethylene glycols. Allergy. 2007;62:92–3.

    Article  PubMed  CAS  Google Scholar 

  69. Ophaswongse S, Maibach HI. Alcohol dermatitis: allergic contact dermatitis and contact urticaria syndrome. Contact Dermatitis. 1994;30:1–6.

    Article  PubMed  CAS  Google Scholar 

  70. Uter W. The European surveillance system of contact allergies (ESSCA): results of patch testing the standard series. J Eur Acad Dermatol Venereol. 2008;22:174–81.

    Google Scholar 

  71. Zug KA, Warshaw EM, Fowler JF, et al. Patch-test results of the North American contact dermatitis group 2005-2006. Dermatitis. 2009;20:149–60.

    PubMed  CAS  Google Scholar 

  72. Barranco Sanz P, Martin Muñoz F, Lopez Serrano C, Martin Esteban M, Ojeda Casas JA. Hypersensitivity to mercuric fluorescein compounds. Allergol Immunopathol. 1989;17:219–22.

    CAS  Google Scholar 

  73. Corrales Torres JL, De Corres F. Anaphylactic hypersensitivity to mercurochrome (merbrominum). Ann Allergy. 1985;54:230–2.

    PubMed  CAS  Google Scholar 

  74. Dooms-Goossens A, Gevers D, Mertens A, Vanderheyden D. Allergic contact urticaria due to chloramine. Contact Dermatitis. 1983;9:319–20.

    Article  PubMed  CAS  Google Scholar 

  75. Kramps JA, van Toorenenbergen AW, Vooren PH, Dijkman JH. Occupational asthma due to inhalation of chloramine-T. II Demonstration of specific IgE antibodies. Int Arch Allergy Appl Immunol. 1981;64:428–38.

    Article  PubMed  CAS  Google Scholar 

  76. Kanerva L, Alanko K, Estlander T, Sihvonen T, Jolanki R. Occupational allergic contact urticaria from chloramine-T solution. Contact Dermatitis. 1997;37:180–1.

    Article  PubMed  CAS  Google Scholar 

  77. Sinaiko R, Heinemann C, Maibach HI. Contact urticaria and anaphylaxis to Chlorhexidine. In: Zhai H, Wilhelm KP, Maibach HI, editors. Dermatotoxicology. Boca Raton: CRC Press; 2007. p. 485–95.

    Chapter  Google Scholar 

  78. Nagendran V, Wicking J, Ekbote A, Onyekwe T, Garvey LH. Ig-E mediated chlorhexidine allergy: a new occupational hazard? Occup Med. 2009;59:270–2.

    Article  Google Scholar 

  79. Calogiuri GF, Di Leo E, Trautmann A, Nettis E, Ferrannini A, Vacca A. Chlorhexidine hypersensitivity: a critical and updated review. J Allergy Ther. 2013;4:141.

    Google Scholar 

  80. Walker S, Chalmers R, Beck M. Contact urticaria due to p-chloro-m-cresol. Br J Dermatol. 2004;151:936–7.

    Article  PubMed  CAS  Google Scholar 

  81. Goncalo M, Goncalo S, Moreno A. Immediate and delayed sensitivity to chlorocresol. Contact Dermatitis. 1987;17:46–7.

    Article  PubMed  CAS  Google Scholar 

  82. Jovanovic M, Karadaglic D, Brkic S. Contact urticaria and allergic contact dermatitis to lidocaine in a patient sensitive to benzocaine and propolis. Contact Dermatitis. 2006;54:124–6.

    Article  PubMed  Google Scholar 

  83. Waton J, Boulanger A, Trechot PH, Schumtz JL, Barbaud A. Contact urticaria from Emla cream. Contact Dermatitis. 2004;51:284–7.

    Article  PubMed  CAS  Google Scholar 

  84. Suzuki T, Kawada A, Yashimoto Y, Isogai R, Aragane Y, Tezuka T. Contact urticaria to ketoprofen. Contact Dermatitis. 2003;48:284–5.

    Article  PubMed  CAS  Google Scholar 

  85. Arroliga ME, Pien L. Penicillin allergy: consider trying penicillin again. Cleveland Clinic J Med. 2003;70:313–26.

    Article  Google Scholar 

  86. Nola RC, Puy R, Deckert K, O’Hehir RE, Douglass JA. Experience with a new commercial skin testing kit to identify IgE-mediated penicillin allergy. Int Med J. 2008;38:357–67.

    Article  CAS  Google Scholar 

  87. Kim MH, Lee JM. Diagnosis and management of immediate hypersensitivity reactions to cephalosporins. Allergy Asthma Immunol Res. 2014;6:485–95.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  88. Romano A, Mayorga C, Torres MJ, Artesani MC, Suau R, Sanchez F, Perez E, Venuti A, Blanca M. Immediate allergic reactions to cephalosporins: cross-reactivity and selective responses. J Allergy Clin Immunol. 2000;106:1177–83.

    Article  PubMed  CAS  Google Scholar 

  89. Kim JE, Kim SH, Jin HJ, Hwang EK, Kim JH, Ye YM, Park HS. IgE sensitization to cephalosporins in health care workers. Allergy Asthma Immunol Res. 2012;4:85–91.

    Article  PubMed  CAS  Google Scholar 

  90. Ariza A, García-Martín E, Salas M, Montañez MI, Mayorga C, et al. Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole. Sci Rep. 2016;6:23845.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  91. Brandão FM, Goossens A. Topical drugs. In: Johansen JD, Frosch PJ, Lepoittevin J-P, editors. Contact dermatitis. 5th ed. Berlin: Springer; 2011. p. 729–62.

    Chapter  Google Scholar 

  92. Rasanen L, Tarvainen K, Makinen-Kiljunen S. Urticaria to hydrocortisone. Allergy. 2001;56:352–3.

    Article  PubMed  CAS  Google Scholar 

  93. Nettis E, Muratore L, Valogiuri G, Ferrannini A, Tursi A. Urticaria to hydrocortisone. Allergy. 2001;56:802–3.

    Article  PubMed  CAS  Google Scholar 

  94. Helaskoski E, Kuuliala O, Aalto-Korte K. Occupational contact urticaria caused by cyclic acid anhydrides. Contact Dermatitis. 2009;60:214–21.

    Article  PubMed  CAS  Google Scholar 

  95. Kanerva L, Jolanki R, Tupasela O, Halmepuro L, Keskinen H, Estlander T, Sysilampi ML. Immediate and delayed allergy from epoxy resins based on diglycidyl ether of bisphenol a. Scand J Work Environ Health. 1991;17:208–15.

    Article  PubMed  CAS  Google Scholar 

  96. Kanerva L, Pelttari M, Jolanki R, Alanko K, Estlander T, Suhonen R. Occupational contact urticarial from diglycidyl ether of bisphenol A epoxy resin. Allergy. 2002;57:1205–7.

    Article  PubMed  CAS  Google Scholar 

  97. Kanerva L, Tokannen J, Jolanki R, Estlander T. Statistical data on occupational contact urticaria. Contact Dermatitis. 1996;35:229–33.

    Article  PubMed  CAS  Google Scholar 

  98. Koopmans AK, Bruynzeel DP. Is PPD a useful screening agent? Contact Dermatitis. 2003;48:89–92.

    Article  PubMed  CAS  Google Scholar 

  99. Seidenari S, Mantovani L, Manzini BM, Pignatti M. Cross-sensitizations between azo dyes and para-amino compound. Contact Dermatitis. 1997;36:91–6.

    Article  PubMed  CAS  Google Scholar 

  100. Uter W, Geier J, Lessmann H, Hausen BM. Contact allergy to disperse blue 106 and disperse blue 124 in german and austrian patients, 1995 to 1999. Contact Dermatitis. 2001;44:173–7.

    Article  PubMed  CAS  Google Scholar 

  101. Wong GA, King CM. Immediate-type hypersensitivity and allergic contact dermatitis due to para-phenylenediamine in hair dye. Contact Dermatitis. 2003;48:166.

    Article  PubMed  CAS  Google Scholar 

  102. Sosted H, Agner T, Andersen KE, Menné T. 55 cases of allergic reactions to hair dye: a descriptive consumer complaint-based study. Contact Dermatitis. 2002;47:299–303.

    Article  PubMed  CAS  Google Scholar 

  103. Goldberg BJ, Hermnn FF, Hirata I. Systemic anaphylaxis due ton an oxidation product of p-phenylenediamine in a hair dye. Ann Allergy. 1987;58:205–8.

    PubMed  CAS  Google Scholar 

  104. Helgesen AL, Austad J. Contact urticaria from aluminium and nickel in the same patient. Contact Dermatitis. 1997;37:303–4.

    Article  PubMed  CAS  Google Scholar 

  105. Kreciscz B, Kiec-Swierczynska M, Krawczyk P, Chomiczewska D, Palczynski C. Cobalt-induced anaphylaxis, contact urticaria and delayed allergy I a ceramics decorator. Contact Dermatitis. 2009;60:173–4.

    Article  Google Scholar 

  106. Bergman A, Svedberg U, Nilsson E. Contact urticaria with anaphylactic reactions caused by occupational exposure to iridium salt. Contact Dermatitis. 1995;32:14–7.

    Article  PubMed  CAS  Google Scholar 

  107. Estlander T, Kanerva L, Tupasela O, Keskinen H, Jolanki R. Immediate and delayed allergy to nickel with contact urticaria, rhinitis, asthma and contact dermatitis. Clin Exp Allergy. 1993;23:306–10.

    Article  PubMed  CAS  Google Scholar 

  108. Cristaudo A, Sera F, Severino V, De Rocco M, Di Lella E, Picardo M. Occupational hypersensitivity to metal salts, including platinum, in the secondary industry. Allergy. 2005;60:159–64.

    Article  PubMed  CAS  Google Scholar 

  109. Schena D, Barba A, Costa G. Occupational contact urticaria due to cisplatin. Contact Dermatitis. 1996;34:220–1.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Dermatochemistry Laboratory, Institut de Chimie de Strasbourg (CNRS UMR 7177), Université de Strasbourg, Strasbourg, France

    Elena Giménez-Arnau

Authors
  1. Elena Giménez-Arnau
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Elena Giménez-Arnau .

Editor information

Editors and Affiliations

  1. Hospital del Mar - Institut Mar d’Investigacions Mediques, Universitat Autònoma de Barcelona (UAB), Department of Dermatology, Barcelona, Spain

    Ana M. Giménez-Arnau

  2. Department of Dermatology, University of California San Francisco, San Francisco, California, USA

    Howard I. Maibach

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Giménez-Arnau, E. (2018). Immediate Skin Contact Reactions Induced by Chemicals. In: Giménez-Arnau, A., Maibach, H. (eds) Contact Urticaria Syndrome. Updates in Clinical Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-89764-6_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-89764-6_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-89763-9

  • Online ISBN: 978-3-319-89764-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation