Abstract
Hypertrophic cardiomyopathy (HCM) is a heterogeneous disease process that leads to variable clinical presentations and outcomes. Many individuals with HCM will remain asymptomatic or only mildly symptomatic throughout life and require no medical intervention. Identification and treatment of symptomatic and high-risk patients and their families remains the cornerstone of management. Indicated treatment is aimed at three interrelated processes of heart failure, sudden cardiac death, and atrial fibrillation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Maron BJ, Maron MS. Hypertrophic cardiomyopathy. Lancet. 2013;381(9862):242–55.
Maron BJ, Maron MS, Semsarian C. Genetics of hypertrophic cardiomyopathy after 20 years: clinical perspectives. J Am Coll Cardiol. 2012;60(8):705–15.
Maron MS, et al. Hypertrophic cardiomyopathy phenotype revisited after 50 years with cardiovascular magnetic resonance. J Am Coll Cardiol. 2009;54(3):220–8.
Maron MS, Lesser JR, Maron BJ. Management implications of massive left ventricular hypertrophy in hypertrophic cardiomyopathy significantly underestimated by echocardiography but identified by cardiovascular magnetic resonance. Am J Cardiol. 2010;105(12):1842–3.
Maron MS, et al. Prevalence, clinical significance, and natural history of left ventricular apical aneurysms in hypertrophic cardiomyopathy. Circulation. 2008;118(15):1541–9.
Sherrid MV, et al. An echocardiographic study of the fluid mechanics of obstruction in hypertrophic cardiomyopathy. J Am Coll Cardiol. 1993;22(3):816–25.
Carasso S, et al. Diastolic myocardial mechanics in hypertrophic cardiomyopathy. J Am Soc Echocardiogr. 2010;23(2):164–71.
Maron MS, et al. The case for myocardial ischemia in hypertrophic cardiomyopathy. J Am Coll Cardiol. 2009;54(9):866–75.
Biagini E, et al. Prognostic implications of the Doppler restrictive filling pattern in hypertrophic cardiomyopathy. Am J Cardiol. 2009;104(12):1727–31.
McLeod CJ, et al. Outcome of patients with hypertrophic cardiomyopathy and a normal electrocardiogram. J Am Coll Cardiol. 2009;54(3):229–33.
Gersh BJ, et al. 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2011;58(25):2703–38.
Adabag AS, et al. Occurrence and frequency of arrhythmias in hypertrophic cardiomyopathy in relation to delayed enhancement on cardiovascular magnetic resonance. J Am Coll Cardiol. 2008;51(14):1369–74.
Maron MS, et al. Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction. Circulation. 2006;114(21):2232–9.
Ommen SR, et al. Long-term effects of surgical septal myectomy on survival in patients with obstructive hypertrophic cardiomyopathy. J Am Coll Cardiol. 2005;46(3):470–6.
Nagueh SF, et al. Alcohol septal ablation for the treatment of hypertrophic obstructive cardiomyopathy. A multicenter North American registry. J Am Coll Cardiol. 2011;58(22):2322–8.
Agarwal S, et al. Updated meta-analysis of septal alcohol ablation versus myectomy for hypertrophic cardiomyopathy. J Am Coll Cardiol. 2010;55(8):823–34.
Olivotto I, et al. Impact of atrial fibrillation on the clinical course of hypertrophic cardiomyopathy. Circulation. 2001;104(21):2517–24.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Slyngstad, T.J., Cove, C.J. (2018). Hypertrophic Cardiomyopathy. In: Mieszczanska, H., Budzikowski, A. (eds) Cardiology Consult Manual. Springer, Cham. https://doi.org/10.1007/978-3-319-89725-7_14
Download citation
DOI: https://doi.org/10.1007/978-3-319-89725-7_14
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-89724-0
Online ISBN: 978-3-319-89725-7
eBook Packages: MedicineMedicine (R0)