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Orthopedic Biomaterials pp 243–286Cite as

Platelet Rich Plasma: Biology and Clinical Usage in Orthopedics

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Abstract

Biological research in the areas of skeletal, cartilaginous, tendinous, and muscular tissues has led to the advancement of various products designed to augment healing. Platelet-rich plasma (PRP) has been in clinical use and researched since the 1970s because of its regenerative properties. In this chapter, we will first define PRP and its components and discuss various methods of preparation and isolation. The second section will focus on the clinical applications of PRP on tissue specific pathologies including tendinopathy, ligamentous injuries, osteoarthritis, and muscle injuries in the field of orthopedic surgery and sports medicine. Lastly, the latest progress in PRP research will be briefly listed and some promising future directions will be discussed.

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Authors and Affiliations

  1. Musculoskeletal Growth & Regeneration Laboratory, Department of Orthopedics Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA

    Dukens LaBaze & Hongshuai Li

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  1. Dukens LaBaze
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  2. Hongshuai Li
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Correspondence to Hongshuai Li .

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Editors and Affiliations

  1. Department of Orthopedics School of Medicine, West Virginia University, Morgantown, West Virginia, USA

    Bingyun Li

  2. Department of Chemical Engineering, Northeastern University, Boston, Massachusetts, USA

    Thomas Webster

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LaBaze, D., Li, H. (2018). Platelet Rich Plasma: Biology and Clinical Usage in Orthopedics. In: Li, B., Webster, T. (eds) Orthopedic Biomaterials . Springer, Cham. https://doi.org/10.1007/978-3-319-89542-0_12

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