Proteomic and Metabolomic Profile of Semen and Seminal Plasma in Varicocele

  • Manesh Kumar Panner Selvam
  • Ashok AgarwalEmail author


Proteomics and metabolomics are now the promising omics techniques for biomarker screening providing complete information on molecular and metabolic processes associated with male infertility. Varicocele is a hot topic of interest in the field of male infertility, and a search for appropriate diagnostic and therapeutic biomarker is still continuing. In this chapter, we discuss the proteomic profile in sperm and seminal plasma of varicocele patients and present an in-depth look into the metabolomic studies associated with male infertility.


Metabolomics Proteomics Sperm Seminal plasma Varicocele 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.American Center for Reproductive Medicine, Department of UrologyCleveland ClinicClevelandUSA

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