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Epilepsy Imaging

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The Neuroimaging of Brain Diseases

Part of the book series: Contemporary Clinical Neuroscience ((CCNE))

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Abstract

Epilepsy is one of the most frequent chronic neurological disorder. The role of neuroimaging is crucial in identifying the causal lesion, as its characterization may play a major role for referring the patients to surgery. This chapter reviews the role of MRI in epilepsy, with a special focus on focal intractable epilepsies. A standard protocol is ineffective for epilepsy imaging. By contrast, an optimized protocol carried out by a neuroradiologist experienced in epilepsy imaging and guided by clinical and electroclinical data on a high field magnet improves the detection of the causal lesion. Advanced sequences such as double inversion recovery, arterial spin labeling, or relaxometry can especially be useful for localizing and characterizing the epileptogenic zone. Hippocampal sclerosis is the most frequent cause of intractable temporal epilepsy, and focal cortical dysplasia is the most frequent extratemporal lesion. Functional MRI and diffusion tensor are crucial when planning a surgical treatment.

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Authors and Affiliations

  1. Department of Radiology, Centre Hospitalier Sainte-Anne, Université Paris Descartes Sorbonne, Paris, France

    Charles Mellerio, Laurence Legrand, Myriam Edjlali, Jean-François Meder & Catherine Oppenheim

  2. Department of imaging, Centre cardiologique du Nord, Saint-Denis, France

    Charles Mellerio

  3. Department of Neurosurgery, Centre de Psychiatrie et Neurosciences, INSERM U894, Paris, France

    Francine Chassoux & Bertrand Devaux

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  1. Charles Mellerio
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  2. Francine Chassoux
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  3. Laurence Legrand
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  4. Myriam Edjlali
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  6. Jean-François Meder
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  7. Catherine Oppenheim
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Correspondence to Charles Mellerio .

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  1. Service de NeuroImagerie CHNO des 15/20, Paris, France

    Christophe Habas

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Mellerio, C. et al. (2018). Epilepsy Imaging. In: Habas, C. (eds) The Neuroimaging of Brain Diseases. Contemporary Clinical Neuroscience. Springer, Cham. https://doi.org/10.1007/978-3-319-78926-2_6

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