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The “Outer Dimensions”: Impulsivity, Anger/Aggressiveness, Activation

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Dimensional Psychopathology

Abstract

The “outer” SVARAD dimensions, impulsivity, anger/aggressiveness, and activation, represent trans-diagnostic psychological and behavioural domains that span traditional categorical boundaries. At the neurobiological level, the fronto-limbic and the fronto-cerebellar circuitry, as well as molecular pathways involving dopamine, serotonin, testosterone, and inflammatory mediators, play a crucial role in mediating the biological underpinnings of these psychopathological dimensions. From a clinical perspective, as the combination of clusters of symptoms differs from patient to patient and gives rise to a wide variety of clinical pictures even among subjects with the same diagnosis, it is important that the clinical features related to impulsivity, anger, aggressiveness, and activation are specifically and multiparametrically investigated and treated. The aim of the present chapter is to discuss the psychopathological aspects, the neurobiological underpinnings, and the clinical implications related to the “outer dimensions” in clinical psychiatry.

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  1. Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy

    Francesco Saverio Bersani & Massimo Pasquini

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  1. Francesco Saverio Bersani
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Correspondence to Francesco Saverio Bersani .

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  1. Department of Human Neurosciences, Policlinico Umberto I Hospital, Sapienza University of Rome, Rome, Italy

    Massimo Biondi

  2. Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy

    Massimo Pasquini

  3. Centre for Behavioural Sciences and Mental Health, Italian National Institute of Health, Rome, Italy

    Angelo Picardi

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Bersani, F.S., Pasquini, M. (2018). The “Outer Dimensions”: Impulsivity, Anger/Aggressiveness, Activation. In: Biondi, M., Pasquini, M., Picardi, A. (eds) Dimensional Psychopathology. Springer, Cham. https://doi.org/10.1007/978-3-319-78202-7_7

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