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Annelida: Oligochaetes (Segmented Worms): Earthworm Immunity, Quo Vadis? Advances and New Paradigms in the Omics Era

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Advances in Comparative Immunology

Abstract

In the last few decades the field of comparative immunology has undergone an enormous amount of progress due to the novel research tools introduced and the expanding amount of transcriptomic information. Recently, the various “omics” approaches have covered every scientific field of biomedical research.

Earthworms as ecologically prominent organisms are used in different research areas of biological and environmental sciences. In-depth research on the immune components of earthworms is now showing rapid progress, but the precise molecular data on this “non-classical” model organism are still relatively limited compared to those from “classical” invertebrate model (e.g., Drosophila, Caenorhabditis elegans) species. In fact, earthworm immunity possesses many common characteristics with other invertebrate organisms but also harbors some unique features.

In this chapter we briefly summarize our recent findings, concentrating on the cellular components of earthworm immunity applying inhouse-developed monoclonal antibodies. Furthermore, we discuss several fast-advancing scientific fields that rely on different omics data (e.g., transcriptome, epigenome, microbiome, and regenerative biology) and those that are relatively under-represented in invertebrate (earthworm) immunity.

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Acknowledgments

We acknowledge the financial support of Medical School Research Foundation, University of Pécs (PTE-ÁOK-KA 2017/04), the János Bolyai Research Scholarship of the Hungarian Academy of Sciences (PE). We are grateful to Krisztina Kovács (Department of Medical Microbiology and Immunology, University of Pécs, Hungary) for providing her skill and expertise in identification of the isolated microorganisms. The present scientific contribution is dedicated to the 650th anniversary of the foundation of the University of Pécs, Hungary.

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  1. Department of Immunology and Biotechnology, Clinical Center, University of Pécs, Pécs, Hungary

    Péter Engelmann

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  1. Péter Engelmann
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  2. Kornélia Bodó
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  3. József Najbauer
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  4. Péter Németh
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Correspondence to Péter Engelmann .

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  1. Laboratory of Comparative Immunology, Department of Neurobiology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA

    Edwin L. Cooper

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Engelmann, P., Bodó, K., Najbauer, J., Németh, P. (2018). Annelida: Oligochaetes (Segmented Worms): Earthworm Immunity, Quo Vadis? Advances and New Paradigms in the Omics Era. In: Cooper, E. (eds) Advances in Comparative Immunology. Springer, Cham. https://doi.org/10.1007/978-3-319-76768-0_6

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