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Preparation of Polymeric and Composite Scaffolds by 3D Bioprinting

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Osteochondral Tissue Engineering

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1058))

Abstract

Over the recent years, the advent of 3D bioprinting technology has marked a milestone in osteochondral tissue engineering (TE) research. Nowadays, the traditional used techniques for osteochondral regeneration remain to be inefficient since they cannot mimic the complexity of joint anatomy and tissue heterogeneity of articular cartilage. These limitations seem to be solved with the use of 3D bioprinting which can reproduce the anisotropic extracellular matrix (ECM) and heterogeneity of this tissue. In this chapter, we present the most commonly used 3D bioprinting approaches and then discuss the main criteria that biomaterials must meet to be used as suitable bioinks, in terms of mechanical and biological properties. Finally, we highlight some of the challenges that this technology must overcome related to osteochondral bioprinting before its clinical implementation.

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Authors and Affiliations

  1. Institute of Polymer Science and Technology-ICTP-CSIC, Madrid, Spain

    Ana Mora-Boza & María Luisa Lopez-Donaire

  2. CIBER, Health Institute Carlos III, Madrid, Spain

    Ana Mora-Boza

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  1. Ana Mora-Boza
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  2. María Luisa Lopez-Donaire
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Correspondence to Ana Mora-Boza .

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Editors and Affiliations

  1. 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Barco, Guimarães, Portugal

    J. Miguel Oliveira

  2. 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Barco, Guimarães, Portugal

    Sandra Pina

  3. 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Barco, Guimarães, Portugal

    Rui L. Reis

  4. Polymeric Nanomaterials and Biomaterials Department, Institute of Polymer Science and Technology, Spanish Council for Scientific Research (CSIC), Madrid, Spain

    Julio San Roman

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Mora-Boza, A., Lopez-Donaire, M.L. (2018). Preparation of Polymeric and Composite Scaffolds by 3D Bioprinting. In: Oliveira, J., Pina, S., Reis, R., San Roman, J. (eds) Osteochondral Tissue Engineering. Advances in Experimental Medicine and Biology, vol 1058. Springer, Cham. https://doi.org/10.1007/978-3-319-76711-6_10

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