Treatment of Neuropsychiatric Systemic Lupus Erythematosus

  • Tetsuji Sawada


Systemic lupus erythematosus includes a wide range of neuropsychiatric manifestations, in which various autoantibodies and cytokines could play a pathophysiologic role. The key drugs used in the treatment of neuropsychiatric systemic lupus erythematosus include corticosteroids and immunosuppressive agents to suppress the underlying inflammatory pathology, antiplatelet and antithrombotic agents in the context of thrombosis mediated by antiphospholipid antibodies, and agents for symptomatic treatment of individual neuropsychiatric manifestations, such as antiepileptic drugs for seizures and antipsychotic drugs for lupus psychosis.


Treatment Corticosteroids Cyclophosphamide Antiplatelet and anticoagulant drugs Symptomatic treatment 


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of RheumatologyTokyo Medical University HospitalTokyoJapan

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