Abstract
Bone marrow scan is mainly used in conjunction with radiolabeled leukocyte imaging to differentiate uptake due to infection from the normal bone marrow [1]. It can also be used to assess bone marrow expansion or depletion, extramedullary hematopoiesis, and bone marrow defects or infarctions and for planning radiation therapy in oncologic patients [2].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Palestro CJ, Love C, Tronco GG, Tomas MB, Rini JN (2006) Combined labeled leukocyte and technetium 99m sulfur colloid bone marrow imaging for diagnosing musculoskeletal infection. Radiographics 26(3):859–870
Bronn LJ, Paquelet JR, Tetalman MR (1980) Intrathoracic extramedullary hematopoiesis: appearance on 99mTc sulfur colloid marrow scan. AJR Am J Roentgenol 134:1254–1255
Siddiqui AR, Oseas RS, Wellman HN, Doerr DR, Baehner RL (1979) Evaluation of bone-marrow scanning with technetium-99m sulfur colloid in pediatric oncology. J Nucl Med 20:379–386
Elgazzar AH (2017) Bone marrow imaging. In: Elgazzar AH (ed) Orthophedic nuclear medicine. Springer, pp 309–310
Vogler JB 3rd, Murphy WA (1988) Bone marrow imaging. Radiology 168:679–693
Valk PE, Guille J (1984) Measurement of splenic function with heat-damaged RBCs: effect of heating conditions: concise communication. J Nucl Med 25:965–968
Ehrlich CP, Papanicolaou N, Treves S, Hurwitz RA, Richards P (1982) Splenic scintigraphy using Tc-99m-labeled heat-denatured red blood cells in pediatric patients: concise communication. J Nucl Med 23:209–213
MacDonald A, Burrell S (2008) Infrequently performed studies in nuclear medicine: part 1. J Nucl Med Technol 36:132–143
Juergensen PH, Rizvi H, Caride VJ, Kliger AS, Finkelstein FO (1999) Value of scintigraphy in chronic peritoneal dialysis patients. Kidney Int 55:1111–1119
Tun KN, Tulchinsky M (2012) Pericatheter leak in a peritoneal dialysis patient: SPECT/CT diagnosis. Clin Nucl Med 37:625–628
Chen YC, Su YC, Chiu JS, Wei CK, Wang YF (2010) Peritoneo-scrotal shunting diagnosed by Tc-99m DTPA SPECT/CT imaging. Kidney Int 78:523
Van den Eeckhaut AC, Villeirs GM, Van de Wiele C, Versijpt JJ, Pattyn P et al (1999) Laparoscopic adjustable silicone gastric banding leakage assessed by 99mTc-pertechnetate scintigraphy. J Nucl Med 40:783–785
Van Den Bossche B, Goethals I, Dierckx RA, Villeirs G, Pattyn P et al (2002) Leakage assessment in adjustable laparoscopic gastric banding: radiography versus (99m)Tc-pertechnetate scintigraphy. Eur J Nucl Med Mol Imaging 29:1128–1131
Weiss H, Peer R, Nehoda H, Labeck B, Bonatti H et al (2001) Improved scintigraphic assessment of occult leakages in adjustable gastric bands using 99mTc-labelled human albumin colloid. Obes Surg 11:502–506
Mittermair RP, Weiss HG, Nehoda H, Peer R, Donnemiller E et al (2003) Band leakage after laparoscopic adjustable gastric banding. Obes Surg 13:913–917
Miller K, Rettenbecher L, Hell E (1996) Adjustments and leak detection of the adjustable silicone gastric band (ASGB) and Lap-Band™ adjustable gastric band (LAGB) system. Obes Surg 6:406–411
Von Denffer H, Dressler J, Pabst HW (1984) Lacrimal dacryoscintigraphy. Semin Nucl Med 14:8–15
Brown M, El Gammal TAM, Luxenburg MN, Eubig C (1981) The value, limitations, and applications of nuclear dacryocystography. Semin Nucl Med 11:250–257
Detorakis ET, Zissimopoulos A, Ioannakis K, Kozobolis VP (2014) Lacrimal outflow mechanisms and the role of scintigraphy: current trends. World J Nucl Med 13:16–21
Recommended methods for measurement of red-cell and plasma volume: International Committee for Standardization in Haematology (1980) J Nucl Med 21:793–800
Dworkin HJ, Premo M, Dees S (2007) Comparison of red cell and whole blood volume as performed using both chromium-51-tagged red cells and iodine-125-tagged albumin and using I-131-tagged albumin and extrapolated red cell volume. Am J Med Sci 334:37–40
Margouleff D (2013) Blood volume determination, a nuclear medicine test in evolution. Clin Nucl Med 38:534–537
McMullin MF (2008) The classification and diagnosis of erythrocytosis. Int J Lab Hematol 30:447–459
Isbister JP (1987) The contracted plasma volume syndromes (relative polycythaemias) and their haemorheological significance. Baillieres Clin Haematol 1:665–693
Desai AG, Thakur ML (1985) Radiopharmaceuticals for spleen and bone marrow studies. Semin Nucl Med 15:229–238
Dawry FP, Rothenberg SP, Bierman L, Maayan ML (1988) Splenic sequestration of red blood cells: a computerized approach using two radionuclides. J Nucl Med Technol 16:185–186
Recommended method for radioisotope red-cell survival studies. International Committee for Standardization in Haematology (1980) Br J Haematol 45:659–666
Elgazzar AH (2014) Nuclear hematology. In: Elgazzar AH (ed) Synopsis of pathophysiology in nuclear medicine. Springer, p 300
Perrotta S, Gallagher PG, Mohandas N (2008) Hereditary spherocytosis. Lancet 372:1411–1426
Valent P, Lechner K (2008) Diagnosis and treatment of autoimmune haemolytic anaemias in adults: a clinical review. Wien Klin Wochenschr 120:136–151
Recommended Method for Indium-111 Platelet Survival Studies. International Committee for Standardization in Hematology. Panel on Diagnostic Applications of Radionuclides (1988) J Nucl Med 29:564–566
Recommended methods for Radioisotope Platelet Survival Studies. The Panel on Diagnostic Application of Radioisotopes in Hematology, International Committee for Standardization in Hematology (1977) Blood 150:1137–1144
Oriuchi N, Korkmaz M, Kim EE, Delpassand ES, Wong F et al (1998) Role of indium-111 labelled platelet scintigraphy in the management of thrombocytopenic patients with malignant neoplasms. Eur J Nucl Med 25:247–252
Gauer RL, Braun MM (2012) Thrombocytopenia. Am Fam Physician 85:612–622
Kistangari G, McCrae KR (2013) Immune thrombocytopenia. Hematol Oncol Clin North Am 27:495–520
Kuipers EJ, Brouwers TM, Hazenberg HJ (1991) Renal trapping of In-111 troponolate labeled platelets in thrombotic thrombocytopenic purpura. Clin Nucl Med 16:506–508
Suga K, Nishigauchi K, Shimizu K, Kume N, Matsunaga N et al (1997) SPECT with In-111 autologous platelets to detect residual splenic tissue in two patients with relapsed thrombocytopenia. Clin Nucl Med 22:141–146
Provan D, Stasi R, Newland AC, Blanchette VS, Bolton-Maggs P et al (2010) International consensus report on the investigation and management of primary immune thrombocytopenia. Blood 115:168–186
Mettler FA Jr, Guibertau MJ (1998) Essentials of nuclear medicine imaging. Gastrointestinal Tract, 4th edn. WB Saunders, Philadelphia, p 281
Briedis D, McIntyre PA, Judisch J, Wagner HN Jr (1973) An evaluation of a dual-isotope method for the measurement of vitamin B 12 absorption. J Nucl Med 14:135–141
Elgazzar AH (2014) Nuclear hematology. In: Elgazzar AH (ed) Synopsis of pathophysiology in nuclear medicine. Springer, p 304
Carmel R, Sinow RM, Siegel ME et al (1988) Food cobalamin malabsorption occurs frequently in patients with unexplained low serum cobalamin levels. Arch Intern Med 148:1715–1719
Allen LH (2008) Causes of vitamin B12 and folate deficiency. Food Nutr Bull 29(2 Suppl):S20–S34
Elgazzar AH (2014) Nuclear hematology. In: Elgazzar AH (ed) Synopsis of pathophysiology in nuclear medicine. Springer, p 303
Higazy E, Al-Saeedi F, Loutfi I, Heiba S, Kalaoui M et al (2000) The impact of brushing teeth on carbon-14 urea breath test results. J Nucl Med Technol 28:162–164
Society of Nuclear Medicine Procedure Guideline for C-14 Urea Breath Test version 3.0, approved June 23, 2001
Elgazzar AH (2014) Digestive system. In: Elgazzar AH (ed) Synopsis of pathophysiology in nuclear medicine. Springer, p 207
Leide-Svegborn S, Stenström K, Olofsson M, Mattsson S, Nilsson LE et al (1999) Biokinetics and radiation doses for carbon-14 urea in adults and children undergoing the Helicobacter pylori breath test. Eur J Nucl Med 26:573–580
Bentur Y, Matsui D, Koren G (2009) Safety of 14C-UBT for diagnosis of Helicobacter pylori infection in pregnancy. Can Fam Physician 55:479–480
Ahuja V, Bal C, Sharma MP (1998) Can the C-14 urea breath test replace follow-up endoscopic biopsies in patients treated for Helicobacter pylori infection? Clin Nucl Med 23:815–819
Logan RPH (1998) Urea breath tests in the management of Helicobacter pylori infection. Gut 43(suppl I):S47–S50
Elgazzar AH (2017) Bone marrow imaging. In: Elgazzar AH (ed) Ortophedic nuclear medicine. Springer, p 318
Karimi M, Cohan N, Bagheri MH, Lotfi M, Omidvari S et al (2008) A lump on the head. Lancet 372:1436
Taher A, Skouri H, Jaber W, Kanj N (2001) Extramedullary hematopoiesis in a patient with beta-thalassemia intermedia manifesting as symptomatic pleural effusion. Hemoglobin 25:363–368
Urman M, O'Sullivan RA, Nugent RA, Lentle BC (1991) Intracranial extramedullary hematopoiesis. CT and bone marrow scan findings. Clin Nucl Med 16:431–434
Sebes JI, Massie JD, White TJ 3rd, Kraus AP (1984) Pelvic extramedullary hematopoiesis. J Nucl Med 25:209–210
Gunes I, Yilmazlar T, Sarikaya I, Akbunar T, Irgil C (1994) Scintigraphic detection of splenosis: superiority of tomographic selective spleen scintigraphy. Clin Radiol 49:115–117
Massey MD, Stevens JS (1991) Residual spleen found on denatured red blood cell scan following negative colloid scans. J Nucl Med 32:2286–2287
Bidet AC, Dreyfus-Schmidt G, Mas J, Combe J, Milleret P et al (1986) Diagnosis of splenosis: the advantages of splenic scintiscanning with Tc 99m heat-damaged red blood cells. Eur J Nucl Med 12:357–358
Alvarez R, Diehl KM, Avram A, Brown R, Piert M (2007) Localization of splenosis using 99mTc-damaged red blood cell SPECT/CT and intraoperative gamma probe measurements. Eur J Nucl Med Mol Imaging 34:969
Person RE, Bender JM (2000) Hepatic lesion differentiated from accessory spleen by a heat-damaged red blood cell scan. Clin Nucl Med 25:516–518
Cho Y, D’Intini V, Ranganathan D (2010) Acute hydrothorax complicating peritoneal dialysis: a case report. J Med Case Rep 4:355
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Elgazzar, A.H., Sarikaya, I. (2018). Miscellaneous Conditions. In: Nuclear Medicine Companion. Springer, Cham. https://doi.org/10.1007/978-3-319-76156-5_11
Download citation
DOI: https://doi.org/10.1007/978-3-319-76156-5_11
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-76155-8
Online ISBN: 978-3-319-76156-5
eBook Packages: MedicineMedicine (R0)