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Diagnostic Approach

  • Agata Ladić
  • Silvija Čuković-ČavkaEmail author
Chapter
Part of the Clinical Gastroenterology book series (CG)

Abstract

Small-intestinal dysfunction is a common finding in patients with long-standing diabetes. The most frequent clinical symptoms are abdominal bloating, nausea, diarrheal syndrome, constipation, and abdominal pain. Considering the diversity of clinical scenarios in intestinal dysfunction, detection of the cause of gastrointestinal symptoms is crucial for decreasing morbidity and mortality in diabetic patients. Differential diagnostic procedures demand the taking into consideration of dysmotility, small intestinal infection, celiac disease, inflammatory bowel disease, amyloidosis, intestinal lymphangiectasia, intestinal lymphoma, lactose intolerance, small bowel obstruction, tropical sprue, Whipple’s disease, tumors of the small intestine, angioneurotic edema, exocrine pancreatic insufficiency and bile salt diarrhea. Prior to starting investigations it is necessary to exclude iatrogenic cause of the symptoms, focusing on the drug history. A multidisciplinary approach is necessary for diagnosis and treatment of diabetic patients with symptoms of small-intestine enteropathy.

Keywords

Diabetes Small intestine Diabetic enteropathy Dysmotility Differential diagnosis Endoscopy Stool culture Fecal calprotectin Celiac disease 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of Gastroenterology and HepatologyUniversity Hospital Center ZagrebZagrebCroatia
  2. 2.University of Zagreb School of MedicineZagrebCroatia

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