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Approach to Esophageal Motility Disorders

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A Mastery Approach to Complex Esophageal Diseases

Abstract

Esophageal motility disorders are a broad category of diseases with a variety of symptoms, ranging from dysphagia to chest pain. The pathophysiology is not always fully understood, but may involve alterations in inhibitory or excitatory innervation of the smooth muscle of the distal esophagus and LES. High-resolution manometry is the gold standard for its diagnosis, and the Chicago classification offers an organizational framework for better evaluation and management. Major disorders of motility are generally pathologic, and include achalasia, EGJOO, DES, hypertensive esophagus, and diseases of absent peristalsis, such as scleroderma. Treatments are targeted at the particular diagnosis. In achalasia, endoscopic and surgical options are preferred. For the remaining motility diagnoses, medical management forms the mainstay of treatment, which can be limited by side effect profiles.

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Author information

Authors and Affiliations

  1. Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Alison Goldin M.D., M.P.H.

  2. VA Boston Healthcare System, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Wai-Kit Lo M.D., M.P.H.

Authors
  1. Alison Goldin M.D., M.P.H.
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  2. Wai-Kit Lo M.D., M.P.H.
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Corresponding author

Correspondence to Wai-Kit Lo M.D., M.P.H. .

Editor information

Editors and Affiliations

  1. Nebraska Medical Center, University of Nebraska Medical Center, Omaha, Nebraska, USA

    Dmitry Oleynikov

  2. Harvard Medical School, West Roxbury, Massachusetts, USA

    P. Marco Fisichella

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Goldin, A., Lo, WK. (2018). Approach to Esophageal Motility Disorders. In: Oleynikov, D., Fisichella, P. (eds) A Mastery Approach to Complex Esophageal Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-75795-7_5

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  • DOI: https://doi.org/10.1007/978-3-319-75795-7_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-75794-0

  • Online ISBN: 978-3-319-75795-7

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