Central Blood Pressure and Prehypertension

  • Charalambos VlachopoulosEmail author
  • Dimitrios Terentes-Printzios
  • Dimitrios Tousoulis
Part of the Updates in Hypertension and Cardiovascular Protection book series (UHCP)


Measurement of blood pressure is one of the most important and powerful clinical tools in clinical practice. Assessment of central blood pressures makes its way from the research field to the clinical field. There are still answers that remain to be answered concerning the incremental predictive ability of central blood pressures over peripheral blood pressures, as well as the possible role of the central BP-guided therapy in everyday practice. Prehypertensive subjects lack guidance from randomized studies and their management is based on data from hypertensive patients or from the general population. Therefore, prehypertension could be a breeding ground for central pressures in order to improve our understanding, as well as the management of this population. Although the predictive ability of central pressures for clinical endpoints in the context of hypertension is not currently substantiated, medium-sized studies have shown a small advantage of central pressures compared to peripheral blood pressures at least as far as intermediate endpoints are concerned. Research on the importance of central pressures in the context of prehypertension should be encouraged.


Prehypertension Central blood pressures Arterial stiffness Augmentation index Aortic hemodynamics 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  • Charalambos Vlachopoulos
    • 1
    Email author
  • Dimitrios Terentes-Printzios
    • 1
  • Dimitrios Tousoulis
    • 1
  1. 1.Hypertension and Cardiometabolic Unit, First Department of Cardiology, Hippokration Hospital, Medical SchoolNational and Kapodistrian University of AthensAthensGreece

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