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Local Treatment of Brain Tumors and the Blood-Brain Barrier

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Emerging Electromagnetic Technologies for Brain Diseases Diagnostics, Monitoring and Therapy

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Abstract

Since the half of the past century, attempts to locally treat intracranial neoplasms have grown. From pioneering interstitial seeds of various materials (radioactive, non-radioactive) with or without the application of ElectroMagnetic Field (EMF), recently new interest was elicited by the possibilities offered by the nanotechnologies. The blocking activity of the Blood-Brain Barrier (BBB) represents main problem for every treatment of brain neoplasms. Shortly, here we summarize some aspects of the blood-brain barrier problem in the perspective of more efficient therapeutic approaches, like the use of nanoparticle and their theranostic possibilities.

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Notes

  1. 1.

    Method that do not require an invasive surgical procedure or intracranial interventions

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Aknowledgements

The Authors thank the grants RVO 61388971, MSMT COST CZ LD 15135, UniCredit Bank CZ, Iginio Longo, Tristano Testa and CAMIC CZ Fund. This work was developed in the framework of COST Action MiMed TD1301 WG2.

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  1. Czech Academy of Sciences, Prague, Czech Republic

    Lenka Rajsiglova & Luca Vannucci

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  1. Lenka Rajsiglova
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  2. Luca Vannucci
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Correspondence to Luca Vannucci .

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Editors and Affiliations

  1. Institute for Electromagnetic Sensing of the Environment, National Research Council of Italy (CNR), Naples, Italy

    Lorenzo Crocco

  2. Department of Mathematics and Engineering Sciences, Hellenic Military Academy, Vari, Athens, Greece

    Irene Karanasiou

  3. Department of Anesthesiology and Neurology, Duke University, Durham, North Carolina, USA

    Michael L James

  4. Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências, Universidade de Lisboa, Lisbon, Portugal

    Raquel Cruz Conceição

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Rajsiglova, L., Vannucci, L. (2018). Local Treatment of Brain Tumors and the Blood-Brain Barrier. In: Crocco, L., Karanasiou, I., James, M., Conceição, R. (eds) Emerging Electromagnetic Technologies for Brain Diseases Diagnostics, Monitoring and Therapy. Springer, Cham. https://doi.org/10.1007/978-3-319-75007-1_7

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