Direct Catalytic Synthesis of C(Sp2)–C(Sp3) Atropisomers with Simultaneous Control of Central and Axial Chirality

  • Nicola Di Iorio
Part of the Springer Theses book series (Springer Theses)


In the previous chapter, we discussed about the synthesis of axially chiral compounds using an indirect method to generate a stereogenic axis. The key point was to break the symmetry of a molecule and “reveal” the blocked rotation of a single sp2–sp2 bond.


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Industrial Chemistry “Toso Montanari”University of BolognaBolognaItaly

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