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Atlas of Mohs and Frozen Section Cutaneous Pathology pp 203–211Cite as

Immunohistochemistry Applications

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Abstract

Immunohistochemistry can be applied judiciously in the delineation of tumoral histiogenesis and the extent of lesional involvement in frozen section pathology. Among the more important immunostains and applications are the use of the MART-1 stain in melanoma, cytokeratin immunostain in cutaneous epithelial malignancy and Ber-EP4 in basal cell carcinoma.

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Bibliography

  1. Bricca GM, Brodland DG, Zitelli JA. Immunostaining melanoma frozen sections: the 1-hour protocol. Dermatol Surg. 2004;30:403–8.

    PubMed  Google Scholar 

  2. Cherpelis BS, Logan T, Ladd S. 19 minute rapid cytokeratin immunostaining of nonmelanoma skin cancer in mohs micrographic surgery. Dermatol Surg (accepted for publication).

    Google Scholar 

  3. Cherpelis BS, Moore R, Ladd S, et al. Comparison of MART-1 frozen sections to permanent sections using a rapid 19 minute protocol. Dermatol Surg (accepted for publication).

    Google Scholar 

  4. Mondragon RM, Barrett TL. Current Concepts: the use of immunoperoxidase techniques in Mohs micrographic surgery. J Am Acad Dermatol. 2000;43(1):66–71.

    Article  CAS  PubMed  Google Scholar 

  5. Rapini RP. Pitfalls of Mohs micrographic surgery. J Am Acad Dermatol. 1990;22:681–6.

    Article  CAS  PubMed  Google Scholar 

  6. Smeets NW, Stavats-Kooy AJ, Krekels GA, et al. Adjuvant cytokeratin staining in Mohs micrographic surgery for basal cell carcinoma. Dermatol Surg. 2003;29:375–7.

    PubMed  Google Scholar 

  7. Tellechea O, Reis JP, Domingues JC, Baptista AP. Monoclonal antibody Ber EP4 distinguises basal-cell carcinoma from squamous-cell carcinoma of the skin. Am J Dermatopathol. 1993;15(5):452–5.

    Article  CAS  PubMed  Google Scholar 

  8. Zachary CB, Rest EB, Furlong SM, Arcedo PN, et al. Rapid cytokeratin stains enhance the sensitivity of Mohs micrographic surgery for squamous cell carcinoma. J Dermatol Surg Oncol. 1994;20:530–5.

    Article  CAS  PubMed  Google Scholar 

  9. Zalla MJ, Lim KK, Dicuado DJ, Gagnot MM. Mohs micrographic excision of melanoma using immunostains. Dermatol Surg. 2000;26:771–84.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Dermatology, University of South Florida College of Medicine, Tampa, FL, USA

    Basil S. Cherpelis

  2. Department of Dermatology, Pathology, and Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida College of Medicine, Tampa, FL, USA

    L. Frank Glass

  3. Gulf Coast Dermatology, Tampa, FL, USA

    John R. Hamill Jr.

  4. University of South Florida, and Director, Advance Dermatological Surgery, James A. Haley Veterans Hospital, Tampa, FL, USA

    John R. Hamill Jr.

  5. Department of Dermatology and Cutaneous Surgery, University of South Florida College of Medicine, Tampa, FL, USA

    Neil Alan Fenske

Authors
  1. Basil S. Cherpelis
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  2. L. Frank Glass
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  3. John R. Hamill Jr.
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  4. Neil Alan Fenske
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Corresponding author

Correspondence to John R. Hamill Jr. .

Editor information

Editors and Affiliations

  1. College of Medicine, University of South Florida College of Medicine, TAMPA, Florida, USA

    Michael B. Morgan

  2. Suite 404, Spencer Dermatology Suite 404, Saint Petersburg, Florida, USA

    James M. Spencer

  3. Gulf Coast Dermatology, Hudson, Florida, USA

    John R. Hamill, Jr.

  4. Thomas Jefferson University, Sidney Kimmel Medical College Thomas Jefferson University, Philadelphia, Pennsylvania, USA

    Rebecca Thornhill

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Cherpelis, B.S., Frank Glass, L., Hamill, J.R., Fenske, N.A. (2018). Immunohistochemistry Applications. In: Morgan, M., Spencer, J., Hamill, Jr., J., Thornhill, R. (eds) Atlas of Mohs and Frozen Section Cutaneous Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-74847-4_19

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  • DOI: https://doi.org/10.1007/978-3-319-74847-4_19

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-74846-7

  • Online ISBN: 978-3-319-74847-4

  • eBook Packages: MedicineMedicine (R0)

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