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Radiation Effects on the Temporal Bone

  • Christopher D. Frisch
  • Beth M. Beadle
  • Paul W. Gidley
Chapter

Abstract

Radiation therapy is a common technique used in the multimodality treatment of head and neck cancers. Radiation causes cell death by a variety of mechanisms, and it may cause damage to both the target cancer cells and adjacent normal tissues. Radiation delivered directly to the temporal bone, or to neighboring subsites, can result in damage ranging from inflammation and infection to osteoradionecrosis or secondary malignancy. The delivered radiation dose appears to be the primary factor driving the development of these side effects. The pathophysiology of radiotherapy and its dose-response relationship will be discussed for the development of different complications. Treatment of these clinical problems will then be outlined.

Keywords

Radiation Temporal bone Radiation effects Osteoradionecrosis Radiation-associated malignancy Carotid rupture Cochlear implant Chronic otitis media Conductive hearing loss 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Christopher D. Frisch
    • 1
  • Beth M. Beadle
    • 2
  • Paul W. Gidley
    • 3
  1. 1.Department of OtolaryngologyOlmsted Medical CenterRochesterUSA
  2. 2.Department of Radiation OncologyStanford UniversityPalo AltoUSA
  3. 3.Department of Head and Neck SurgeryThe University of Texas M.D. Anderson Cancer CenterHoustonUSA

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