Adenomatous Polyposis Syndromes: Introduction
The adenomatous polyposis of the colorectum is the most frequent polyposis type and a precancerous condition with a high lifetime risk of colorectal cancer (CRC), unless detected early. Currently, at least five different inherited forms can be delineated by molecular genetic analyses. Although all types are defined by multiple adenomas which result in a similar diagnostic and therapeutic approach, a significant clinical variability in terms of number and age at onset and the presence of benign and malignant extraintestinal lesions can be observed.
KeywordsPolyposis coli FAP Gastrointestinal polyposis