Abstract
Enzymes have extremely interesting properties that make them catalysis for a huge number of chemical reactions. These little-reaction machines are commonly applied in chemical engineering processes. There are many different approaches and methods available to improve enzymes activated processes. This paper discusses a possibility to apply them for a rotating magnetic field as a tool in modern chemical engineering to precisely regulate ex vivo and in vivo enzyme activity.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Anton-Leberre V, Haanappel E, Marasaund N et al (2010) Expsoure to high static or pulsed magnetic fields does not affect cellular processes in the yeast Saccharomyces cerevisiae. Bioelectromagnetics 31:28–38
Bahar T, Çelebi SS (2000) Performance of immobilized glucoamylase in a magnetically stabilized fluidized bed reactor (MSFBR). Enzyme Microb Tech 26:28–33
Berendsen WR, Lapin A, Reuss M (2008) Investigations of reaction kinetics for immobilized enzymes–identification of parameters in the presence of diffusion limitation. Biotechnol Prog 22:1305–1312
Bialek W, Bruno WJ, Joseph J et al (1989) Quantum and classical dynamics in biochemical reactions. Photosynth Res 22(1):15–27
Blank M, Soo L (2001) Optimal frequencies for magnetic acceleration of cytochrome oxidase and Na, K-ATPase Reactions. Bioelectrochemistry 53(2):171–174
Bramble JL, Graves DJ, Brodelius P (1990) Plant cell culture using a novel bioreactor: the magnetically stabilized fluidized bed. Biotechnol Prog 6:452–457
Calabrò E, Magazù S (2012) Electromagnetic fields effects on the secondary structure of lysozyme and bioprotective effectiveness of trehalose. Adv Phys Chem 2012, Article ID 970369
Campbell B, Petukh M, Alexov E et al (2014) On the electrostatic properties of homodimeric proteins. J Theor Comput Chem 13(3):1440007
Diamond R (1974) Real–space refinement of the structure of hen egg–white lysozyme. J Mol Biol 82:371–391
Domingues L, Vicente AA, Lima N et al (2000) Applications of yeast flocculation in biotechnological processes. Biotechnol Bioprocess Eng 5:288–305
Dong-Hao Z, Li-Xia Y, Li-Juan P (2013) Parameters affecting the performance of immobilized enzyme. J Chem 2013, Article ID 946248
Eichwald C, Walleczek J (1996) Model for magnetic field effects on radical pair recombination in enzyme kinetics. Biophys J 71:623–631
Gaafar ESA, Hanafy MS, Tohamy EY et al (2008) The effect electromagnetic field on protein molecular structure of E. coli and its pathogenesis. Rom J Biophys 18:145–169
Giardina P, Faraco V, Pezzella C et al (2010) Laccases: a never-ending story. Cell Mol Life Sci 67(3):369–385
Gogate PR, Beenackers AACM, Pandit AB (2000) Multiple-impeller systems with a special emphasis on bioreactors: a critical review. Biochem Eng J 6:109–144
Golovin YI, Gribanovskii SL, Golovin DY et al (2014) Single-domain magnetic nanoparticles in an alternating magnetic field as mediators of local deformation of the surrounding macromolecules. Phys Solid State 56(7):1342
Grissom CB (1995) Magnetic field effects in biology: a survey of possible mechanisms with emphasis on radical-pair recombination. Chem Rev 95(1):3–24
Gusakov AV, Sinitsyn AP, Davydkin IYOV et al (1995) Use of a bioreactor with intense mass transfer for enzymatic hydrolysis of cellulose-containing materials. Appl Biochem Micro 31:310–314
Gusakov AV, Sinitsyn AP, Davydkin IY et al (1996) Enhancement of enzymatic cellulose hydrolysis using a novel type of bioreactor with intensive stirring. Appl Biochem Micro 56:141–153
Hajiani P, Larachi F (2012) Reducing Taylor dispersion in capillary laminar flows using magnetically excited nanoparticles: nanomixing mechanism for micro/nanoscale applications. Chem Eng J 203:492–498
Hajiani P, Larachi F (2013) Giant effective liquid-self diffusion in stagnant liquids by magnetic nanomixing. Chem Eng Process 71:77–82
Holysz L, Szcześ A, Chibowski E (2007) Effects of a static magnetic field on water and electrolyte solutions. J Colloid Interface Sci 316(2):996–1002
Hristov J (2002) Magnetic field assisted fluidization—a unified approach. Part 1: fundamentals and relevant hydrodynamics. Rev Chem Eng 18:295–509
Hristov J (2010) Magnetic field assisted fluidization—a unified approach. Part 8: mass transfer: magnetically assisted bioprocess. Rev Chem Eng 26:55–128
Hristov JY, Ivanova V (1999) Magnetic field assisted bioreactors. Recent Res Dev Ferment Bioeng 2:41–95
Hunt RW, Zavalin A, Bhatnagar A et al (2009) Electromagnetic biostimulation of living cultures for biotechnology, biofuel and bioenergy applications. Int J Mol Sci 10:4515–4558
Jones AR, Hay S, Woodward JR et al (2007) Magnetic field effect studies indicate reduced geminate recombination of the radical pair in substrate-bound adenosylcobalamin-dependent ethanolamine ammonia lyase. J Am Chem Soc 129(50):15718–15727
Kholoov Y (ed) (1974) Influence of magnetic field on biological objects. U.S. Joint Publications Research Service, Arlington, VA
Klyachko NL, Sokolsky-Papkov M, Pothayee N et al (2012) Changing the enzyme reaction rate in magnetic nanosuspensions by a non-heating magnetic field. Angew Chem Int Ed 51:12016–12019
Ledakowicz S (2011) Inżynieria biochemiczna. Wydawnictwo Naukowo Techniczne, Warszawa
Li JY, Wang AJ, Ren NQ et al (2014) Effects of static magnetic field on phosphate buffer solution. Adv Mat Res 953–954:1293–1296
Magazù S, Calabrò E (2011) Studying the electromagnetic-induced changes of the secondary structure of bovine serum albumin and the bioprotective effectiveness of trehalose by Fourier transform infrared spectroscopy. J Phys Chem B 115(21):6818–6826
Mehta J, Bhardwaj N, Bhardwaj SK et al (2016) Recent advances in enzyme immobilization techniques: metal-organic frameworks as novel substrates. Coord Chem Rev 322:30–40
Mei G, Di Venere A, Rosato N et al (2005) The importance of being dimeric. FEBS J 272(1):16–27
Messiha HL, Wongnate T, Chaiyen P et al (2014) Magnetic field effects as a result of the radical pair mechanism are unlikely in redox enzymes. J R Soc Interface 12:20141155
Mizuki T, Watanabe N, Nagaoka Y et al (2010) Activity of an enzyme immobilized on superparamagnetic particles in a rotational magnetic field. Biochem Biophys Res Commun 393(4):779–782
Mizuki T, Sawai M, Nagaoka Y et al (2013) Activity of lipase and chitinase immobilized on superparamagnetic particles in a rotational magnetic field. PLoS One 8(6):e66528
Moffat HK (1991) Electromagnetic stirring. Phys Fluids A 3:1336–1343
Moffat G, Williams RA, Webb C et al (1994) Selective separation in environmental and industrial processes using magnetic carrier technology. Miner Eng 7:1039–1056
Mohamad NR, Marzuki NH, Buang NA et al (2015) An overview of technologies for immobilization of enzymes and surface analysis techniques for immobilized enzymes. Biotechnol Biotechnol Equip 29(2):205–220
Molokov S, Moreau R, Moffat HK (2007) Magnetohydrodynaics. In: Molokov S, Moreau S, Moffatt R, Keith H (eds) Historical evolution and trends. Springer, The Netherlands
Myśliwiec D, Szcześ A, Chibowski S (2016) Influence of static magnetic field on the kinetics of calcium carbonate formation. J Ind Eng Chem 35:400–407
Pringle JR (1981) The Saccharomyces cerevisiae cell cycle. The molecular biology of yeast Saccharomyces: life cycle and inheritance, pp 97–142
Rakoczy R (2010) Enhancement of solid dissolution process under the influence of rotating magnetic field. Chem Eng Process 49:42–50
Rakoczy R, Masiuk S (2010) Influence of transverse rotating magnetic field on enhancement of dissolution process. AIChE J 56:1416–1433
Rakoczy R, Masiuk S (2011) Studies of mixing process induced by a transverse rotating magnetic field. Chem Eng Sci 66:2298–2308
Rakoczy R, Konopacki M, Fijałkowski K (2016) The influence of a ferrofluid in the presence of an external rotating magnetic field on the growth rate and cell metabolic activity of a wine yeast strain. Biochem Eng J 109:43–50
Rakoczy R, Lechowska J, Kordas M et al (2017) Effects of a rotating magnetic field on gas–liquid mass transfer coeffcient. Chem Eng J 327:608–617
Rosensweig RE (1979) Fluidization: hydrodynamics stabilization with a magnetic field. Science 204:57–60
Rumfeldt JA, Galvagnion C, Vassall KA et al (2008) Conformational stability and folding mechanisms of dimeric proteins. Prog Biophys Mol Biol 1:61–84
Ryu KS, Shaikh K, Goluch E et al (2004) Micro magnet stir-bar mixer integrated with parylene microfluidic channels. Lab Chip 4:608–613
Sada E, Katoh S, Shiozawa M et al (1981) Performance of fluidized-bed reactors utilizing magnetic-fields. Biotechnol Bioeng 23:2561–2567
Sakai Y, Taguchi H, Takahashi F (1989) The effect of alternative magnetic field on the pigment ejection from magnetic anisotropic gel beads. B Chem Soc Jpn 62:3207–3210
Sakai Y, Kuwahata M, Takahashi F (1990) The effect of alternating magnetic field on the magnetic anisotropic gel beads immobilized catalase. B Chem Soc Jpn 63:2358–2362
Sakai Y, Kuwahata M, Takahashi F (1992a) Numerical formulation of pigment release from magnetically anisotropic gel beads with respect to the magnetic moment in an alternating magnetic field. B Chem Soc Jpn 65:396–399
Sakai Y, Osada K, Takahashi F et al (1992b) Preparation and properties of immobilized glucoamylase on a magnetically anisotropic carrier comprising a ferromagnetic powder coated by albumin. B Chem Soc Jpn 65:3430–3433
Sakai Y, Tamiya Y, Takahashi F (1994) Enhancement of ethanol formation by immobilized yeast containing iron powder or Ba-ferrite due to eddy current or hysteresis. J Ferment Bioeng 77:169–172
Sakai Y, Oishi A, Takahashi F (1999) Enhancement of enzyme reaction of magnetically anisotropic polyacrylamide gel rods immobilized with ferromagnetic powder in an alternating magnetic field. Biotechnol Bioeng 62:363–367
Sheldon RA, van Pelt S (2013) Enzyme immobilisation in biocatalysis: why, what and how. Chem Soc Rev 42:6223–6235
Sheu SY, Yang DY, Selzle HL, Schlag EW (2003) Energetics of hydrogen bonds in peptides. Proc Natl Acad Sci USA 100(22):12683-12687. 28 October 2003
Singh RK, Tiwari MK, Singh R et al (2013) From protein engineering to immobilization: promising strategies for the upgrade of industrial enzymes. Int J Mol Sci 14:1232–1277
Sinha N, Smith-Gill SJ (2002) Electrostatics in protein binding and function. Curr Protein Pept Sci 3(6):601–614
Sinitsyn AP, Gusakov AV, Davydkin IY et al (1993) A hyperefficient process for enzymatic cellulose hydrolysis in the intensive mass transfer reactor. Biotechnol Lett 15:283–288
Steiner UE, Ulrich T (1989) Magnetic field effects in chemical kinetics and related phenomena. Chem Rev 89:51–147
Szcześ A, Chibowski E, Hołysz L et al (2011) Effects of static magnetic field on electrolyte solutions under kinetic condition. J Phys Chem A 115(21):5449–5452
Szefczyk B, Mulholland AJ, Ranaghan KE et al (2004) Differential transition-state stabilization in enzyme catalysis: quantum chemical analysis of interactions in the chorismate mutase reaction and prediction of the optimal catalytic field. J Am Chem Soc 126(49):16148–16159
Taraban MB, Leshina TV, Anderson MA et al (1997) Magnetic field dependence of electron transfer and the role of electron spin in heme enzymes: horseradish peroxidase. J Am Chem Soc 119:5768–5769
Vaghari H, Jafarizadeh-Malmiri H, Mohammadlou MS et al (2016) Application of in smart enzyme immobilization. Biotechnol Lett 38:223–233
Van den Burg B, Vriend G, Veltman OR et al (1998) Engineering an enzyme to resist boiling. Proc Natl Acad Sci USA
Vangas J, Viesturs U, Fort I (1999) Mixing intensity studies in a pilot plant stirred bioreactor with an electromagnetic drive. Biochem Eng J 3:25–33
Wang Y, Zhe J, Chung BTF et al (2008) A rapid magnetic particle driven micromixer. Microfluid Nanofluid 4:375–389
Webb C, Kang H, Moffat G et al (1996) The magnetically stabilized fluidized bed bioreactor: a tool for improved mass transfer in immobilized enzyme systems? Chem Eng J 61:241–246
Woodward JR (2002) Radical pairs in solution. Prog React Kinet Mech 27:165–207
Xiu GH, Jiang L, Li P (2001) Mass-transfer limitations for immobilized enzyme-catalyzed kinetic resolution of racemate in a fixed-bed reactor. Biotechnol Bioeng 74:29–39
Yang K, Xu NS, Su WW (2010) Co-immobilized enzymes in magnetic chitosan beads for improved hydrolysis of macromolecular substrates under a time-varying magnetic field. J Biotechnol 148(2-3):119-127. 20 July 2010
Zheng M, Su Z, Ji X, Ma G, Wang P, Zhang S (2013) Magnetic field intensified bi-enzyme system with in situ cofactor regeneration supported by magnetic nanoparticles. J Biotechnol 168(2):212-217. 20 October 2013
Acknowledgements
The authors are grateful for the financial support of the National Science Centre Poland within the PRELUDIUM 11 Programme (Grant No. 2016/21/N/ST8/02343).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG
About this paper
Cite this paper
Drozd, R., Wasak, A., Konopacki, M., Kordas, M., Rakoczy, R. (2018). The Influence of Rotating Magnetic Field on Biochemical Processing. In: Ochowiak, M., Woziwodzki, S., Doligalski, M., Mitkowski, P. (eds) Practical Aspects of Chemical Engineering. Lecture Notes on Multidisciplinary Industrial Engineering. Springer, Cham. https://doi.org/10.1007/978-3-319-73978-6_5
Download citation
DOI: https://doi.org/10.1007/978-3-319-73978-6_5
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-73977-9
Online ISBN: 978-3-319-73978-6
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)