Skip to main content

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Falagas ME, Rafailidis PI (2008) Re-emergence of colistin in today’s world of multidrug-resistant organisms: personal perspectives. Expert Opin Investig Drugs 17:973–981

    Article  CAS  PubMed  Google Scholar 

  2. Karaiskos I, Giamarellou H (2014) Multidrug-resistant and extensively drug-resistant Gram-negative pathogens: current and emerging therapeutic approaches. Expert Opin Pharmacother 15:1351–1370

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Kumarasamy KK, Toleman MA, Walsh TR et al (2010) Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis 10:597–602

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Bergen PJ, Landersdorfer CB, Zhang J et al (2012) Pharmacokinetics and pharmacodynamics of ‘old’ polymyxins: what is new? Diagn Microbiol Infect Dis 74:213–223

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Gilbert B, Morrison C (2017) Evaluation of intraventricular colistin utilization: a case series. J Crit Care 40:161–163

    Article  CAS  PubMed  Google Scholar 

  6. Landersdorfer CB, Nation RL (2015) Colistin: how should it be dosed for the critically ill? Semin Respir Crit Care Med 36:126–135

    Article  PubMed  Google Scholar 

  7. Grégoire N, Aranzana-Climent V, Magréault S, Marchand S, Couet W (2017) Clinical pharmacokinetics and pharmacodynamics of colistin. Clin Pharmacokinet 56:1441–1460

    Article  PubMed  Google Scholar 

  8. Plachouras D, Karvanen M, Friberg LE et al (2009) Population pharmacokinetic analysis of colistin methanesulfonate and colistin after intravenous administration in critically ill patients with infections caused by gram-negative bacteria. Antimicrob Agents Chemother 53:3430–3436

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Nation RL, Garonzik SM, Thamlikitkul V et al (2017) Dosing guidance for intravenous colistin in critically-ill patients. Clin Infect Dis 64:565–571

    PubMed  Google Scholar 

  10. Leypoldt JK, Jaber BL, Lysaght MJ, McCarthy JT, Moran J (2003) Kinetics and dosing predictions for daily haemofiltration. Nephrol Dial Transplant 18:769–776

    Article  CAS  PubMed  Google Scholar 

  11. Jeffrey RF, Khan AA, Prabhu P et al (1994) A comparison of molecular clearance rates during continuous hemofiltration and hemodialysis with a novel volumetric continuous renal replacement system. Artif Organs 18:425–428

    Article  CAS  PubMed  Google Scholar 

  12. Elbers PW, Girbes A, Malbrain ML, Bosman R (2015) Right dose, right now: using big data to optimize antibiotic dosing in the critically ill. Anaesthesiol Intensive Ther 47:457–463

    Article  PubMed  Google Scholar 

  13. Martinkova J, Malbrain ML, Havel E, Šafránek P, Bezouška J, Kaška M (2016) A pilot study on pharmacokinetic/pharmacodynamic target attainment in critically ill patients receiving piperacillin/tazobactam. Anaesthesiol Intensive Ther 48:23–28

    Article  PubMed  Google Scholar 

  14. Azad MA, Huang JX, Cooper MA et al (2012) Structure-activity relationships for the binding of polymyxins with human α-1-acid glycoprotein. Biochem Pharmacol 84:278–291

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Dudhani RV, Li J, Nation RL (2009) Plasma binding of colistin involves multiple proteins and is concentration dependent: potential clinical implications. Abstracts of the forty-ninth Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, p 41

    Google Scholar 

  16. Herve F, Gomas E, Duche JC, Tillement JP (1993) Evidence for differences in the binding of drugs to the two main genetic variants of human alpha 1-acid glycoprotein. Br J Clin Pharmacol 36:241–249

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Israili ZH, Dayton PG (2001) Human alpha-1-glycoprotein and its interactions with drugs. Drug Metab Rev 33:161–235

    Article  CAS  PubMed  Google Scholar 

  18. Pea F, Viale P, Pavan F, Furlanut M (2007) Pharmacokinetic considerations for antimicrobial therapy in patients receiving renal replacement therapy. Clin Pharmacokinet 46:997–1038

    Article  CAS  PubMed  Google Scholar 

  19. Mariano F, Leporati M, Carignano P, Stella M, Vincenti M, Biancone L (2015) Efficient removal of colistin A and B in critically ill patients undergoing CVVHDF and sorbent technologies. J Nephrol 28:623–631

    Article  CAS  PubMed  Google Scholar 

  20. Honore PM, Jacobs R, Lochy S et al (2013) Acute respiratory muscle weakness and apnea in a critically ill patient induced by colistin neurotoxicity: key potential role of hemoadsorption elimination during continuous venovenous hemofiltration. Int J Nephrol Renovasc Dis 6:107–111

    Article  PubMed  PubMed Central  Google Scholar 

  21. Honore PM, Jacobs R, Joannes-Boyau O et al (2013) Newly designed CRRT membranes for sepsis and SIRS—a pragmatic approach for bedside intensivists summarizing the more recent advances: a systematic structured review. ASAIO J 59:99–106

    Article  CAS  PubMed  Google Scholar 

  22. Karaiskos I, Friberg LE, Galani L et al (2016) Challenge for higher colistin dosage in critically ill patients receiving continuous venovenous haemodiafiltration. Int J Antimicrob Agents 48:337–341

    Article  CAS  PubMed  Google Scholar 

  23. Verdoodt A, Honore PM, Jacobs R, Van Gorp V, Hubloue I, Spapen HD (2017) High-dose colistin combined with continuous veno-venous haemofiltration for treatment of multidrug-resistant Gram-negative infection in critically ill patients. Intensive Care Med Exp 5(Suppl 2):44-0986 (abst)

    Google Scholar 

  24. Gobin P, Lemaître F, Marchand S, Couet W, Olivier JC (2010) Assay of colistin and colistin methanesulfonate in plasma and urine by liquid chromatography-tandem mass spectrometry. Antimicrob Agents Chemother 54:1941–1948

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Honore PM, Jacobs R, Hendrickx I, De Waele E, Van Gorp V, Spapen HD (2015) Higher colistin dose during continuous renal replacement therapy: look before leaping! Crit Care 19:235

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to P. M. Honore .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this chapter

Cite this chapter

Honore, P.M., Malbrain, M.L.N.G., Spapen, H.D. (2018). Colistin Dosing in Continuous Renal Replacement Therapy. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2018. Annual Update in Intensive Care and Emergency Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-73670-9_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-73670-9_6

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-73669-3

  • Online ISBN: 978-3-319-73670-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics