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Blood Transfusion in Critically Ill Patients with Traumatic Brain Injury

  • A. F. Turgeon
  • F. Lauzier
  • D. A. Fergusson
Part of the Annual Update in Intensive Care and Emergency Medicine book series (AUICEM)

Introduction

Traumatic brain injury (TBI) is the main cause of death in the first half of life and a significant proportion of survivors of severe TBI are left with severe permanent impairment [12]. Not surprisingly, TBI patients also consume the majority of healthcare resources in trauma care [34]. Current management of critically ill patients with TBI focuses on preventing secondary cerebral injuries. Most interventions in the acute phase of care are thus directed at ensuring appropriate brain oxygen delivery (DO2). However, the majority of these interventions are based on very limited rigorous evidence [5], with highly variable within and between center practice. This variation has led to significant outcome differences being observed across centers [2], including regarding the use of red blood cell (RBC) transfusion. RBC transfusion is a common intervention administered in TBI given the high proportion of anemia in this population. Although there has been a move towards...

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • A. F. Turgeon
    • 1
    • 2
  • F. Lauzier
    • 1
    • 2
  • D. A. Fergusson
    • 3
  1. 1.Population Health and Optimal Health Practices Unit (Trauma – Emergency – Critical Care Medicine)CHU de Québec-Université Laval Research CentreQuebecCanada
  2. 2.Department of Critical Care MedicineCHU de Québec-Université LavalQuebecCanada
  3. 3.Clinical Epidemiology ProgramOttawa Hospital Research Institute Centre for Practice-Changing ResearchOttawaCanada

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