Acute Kidney Injury Risk Prediction

  • K. Kashani
Part of the Annual Update in Intensive Care and Emergency Medicine book series (AUICEM)


Acute kidney injury (AKI) is considered one of the most common complications of acute illness, with a substantial impact on patient outcome and hospital costs [1, 2, 3]. It has been reported that higher severity of AKI is associated with more severe short‐ and long‐term mortality and morbidities. In many cases, AKI is a preventable disease. In a recent study, protocolized intervention after cardiac surgery was associated with a considerable reduction in the incidence of AKI [4]. Appropriate preventive measures need to be given in a time‐sensitive manner. A delay in recognition and intervention may result in progression of injury and increase the risk of death, the need for renal replacement therapy (RRT), and likelihood of chronic kidney disease [5].

Currently, the diagnosis of AKI is based on two functional biomarkers of the kidney: serum creatinine and urinary output [6]. Unfortunately, both of these biomarkers have substantial shortcomings in the timely recognition...


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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Division of Pulmonary and Critical Care MedicineMayo ClinicRochesterUSA
  2. 2.Division of Nephrology and HypertensionMayo ClinicRochesterUSA

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