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Electrodiagnosis of Neuromuscular Junction Disorders

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Myasthenia Gravis and Related Disorders

Part of the book series: Current Clinical Neurology ((CCNEU))

Abstract

The electrodiagnostic (EDX) examination in patients with suspected neuromuscular junction (NMJ) disorders requires a sound working knowledge of the physiology and pathophysiology of neuromuscular transmission. The EDX studies that are useful in the evaluation of such patients include (1) motor nerve conduction studies (NCSs), (2) conventional needle electromyography (EMG), (3) repetitive nerve stimulation (RNS), and (4) single-fiber EMG. This chapter reviews the basics of neuromuscular transmission, as it relates to the EDX studies, and discusses in detail the EDX studies and findings in various NMJ disorders.

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Author information

Authors and Affiliations

  1. Department of Neurology, University Hospitals Cleveland Medical Center/Case Western Reserve University, Cleveland, OH, USA

    Christopher David Geiger DO & Bashar Katirji MD, FACP

  2. Neurological Institute, Bowlell Health Center, Cleveland, OH, USA

    Christopher David Geiger DO & Bashar Katirji MD, FACP

Authors
  1. Christopher David Geiger DO
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  2. Bashar Katirji MD, FACP
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Correspondence to Christopher David Geiger DO .

Editor information

Editors and Affiliations

  1. Department of Neurology, George Washington University, Washington, DC, USA

    Henry J. Kaminski

  2. Department of Pharmacology and Physiology, George Washington University, Washington, DC, USA

    Linda L. Kusner

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Geiger, C.D., Katirji, B. (2018). Electrodiagnosis of Neuromuscular Junction Disorders. In: Kaminski, H., Kusner, L. (eds) Myasthenia Gravis and Related Disorders. Current Clinical Neurology. Humana Press, Cham. https://doi.org/10.1007/978-3-319-73585-6_9

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  • DOI: https://doi.org/10.1007/978-3-319-73585-6_9

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  • Publisher Name: Humana Press, Cham

  • Print ISBN: 978-3-319-73584-9

  • Online ISBN: 978-3-319-73585-6

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