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Comparing Different Data Fusion Strategies for Cancer Classification

  • Katarzyna Pojda
  • Michał Jakubczak
  • Sebastian Student
  • Andrzej Świerniak
  • Krzysztof Fujarewicz
Conference paper
Part of the Advances in Intelligent Systems and Computing book series (AISC, volume 721)

Abstract

Automatic cancer diagnosis can be performed based on different types of data sets. Some of them are microarray data, clinical trial data and cytopathological data. Usually class prediction is done by chosen classification method, for example a machine learning algorithm, and uses only one type of the available data. In this work an additional predictive value of a fusion of these three types of data is examined. To perform such research, authors upgrade and use their recently developed Spicy system. Different data fusion strategies have been tested on thyroid cancer data set. The workflow that has been created and the new module of a data fusion implemented in the Spicy system allows to qualify fusion of microarray data, clinical trials data and information about the Bethesda system class as a valuable method of prediction the thyroid nodule malignancy.

Keywords

Cancer classification Feature selection Data fusion Machine learning 

Notes

Acknowledgment

This work was supported by NCBR (Polish National Centre for Research and Development) under grant Strategmed2/267398/4/NCBR/2015 and by Silesian University of Technology. Calculations were performed using the infrastructure supported by the computer cluster Ziemowit (www.ziemowit.hpc.polsl.pl) funded by the Silesian BIO-FARMA project No. POIG.02.01.00-00-166/08 and expanded in the POIG.02.03.01-00-040/13 in the Computational Biology and Bioinformatics Laboratory of the Biotechnology Centre at the Silesian University of Technology.

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Katarzyna Pojda
    • 1
  • Michał Jakubczak
    • 1
  • Sebastian Student
    • 1
  • Andrzej Świerniak
    • 1
  • Krzysztof Fujarewicz
    • 1
  1. 1.Silesian University of TechnologyGliwicePoland

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