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Sleep Disorders

  • Nery A. Diaz
Chapter

Abstract

Sleep disorders are not a normal part of aging, although complaints of difficulty with sleep are not uncommon in late life. The cause of sleep disorders in the elderly is usually multifactorial and often associated with poor health. Aging is correlated with an increase in latency of sleep (the amount of time it takes to fall asleep) and decrease in slow-wave sleep (restorative sleep). Changes in sleep patterns affect men and women differently. The available data for the diagnosis and proper treatment of sleep disorders in older adults is hampered by a lack of controlled studies examining objective sleep measures in the elderly. This chapter summarizes information on epidemiology, sleep physiology, diagnosis, and treatment for sleep disorders in the elderly.

Keywords

Sleep disorders Aging Insomnia Sleep apnea Sleep-related breathing disorders Periodic limb movement disorders 

References

  1. 1.
    AASM: The American Academy of Sleep Medicine - Association for Seep Clinicians and Researchers. http://www.aasmnet.org.
  2. 2.
    Ropper AH, Adams RD, Victor M, Samuels MA. Adams and Victor's principles of neurology. 9th ed. New York: McGraw-Hill Medical; 2009.Google Scholar
  3. 3.
    Fetveit A. Late-life insomnia: a review. Geriatr Gerontol Int. 2009;9(3):220–34.CrossRefPubMedGoogle Scholar
  4. 4.
    Ancoli-Israel S. Sleep and its disorders in aging populations. Sleep Med. 2009;10(Suppl 1):S7–11.CrossRefPubMedGoogle Scholar
  5. 5.
    Vitiello MV, Moe KE, Prinz PN. Sleep complaints cosegregate with illness in older adults: clinical research informed by and informing epidemiological studies of sleep. J Psychosom Res. 2002;53(1):555–9.CrossRefPubMedGoogle Scholar
  6. 6.
    Foley D, Ancoli-Israel S, Britz P, Walsh J. Sleep disturbances and chronic disease in older adults: results of the 2003 National Sleep Foundation Sleep in America Survey. J Psychosom Res. 2004;56(5):497–502.CrossRefPubMedGoogle Scholar
  7. 7.
    Ohayon MM. Epidemiology of insomnia: what we know and what we still need to learn. Sleep Med Rev. 2002;6(2):97–111.CrossRefPubMedGoogle Scholar
  8. 8.
    Zdanys KF, Steffens DC. Sleep disturbances in the elderly. Psychiatr Clin North Am. 2015;38(4):723–41.CrossRefPubMedGoogle Scholar
  9. 9.
    Reynolds CF, Kupfer DJ, Taska LS, Hoch CC, Sewitch DE, Spiker DG. Sleep of healthy seniors: a revisit. Sleep. 1985;8(1):20–9.CrossRefPubMedGoogle Scholar
  10. 10.
    Franklin KA, Lindberg E. Obstructive sleep apnea is a common disorder in the population-a review on the epidemiology of sleep apnea. J Thorac Dis. 2015;7(8):1311–22.PubMedPubMedCentralGoogle Scholar
  11. 11.
    Moe KE, Prinz PN, Vitiello MV, Marks AL, Larsen LH. Healthy elderly women and men have different entrained circadian temperature rhythms. J Am Geriatr Soc. 1991;39(4):383–7.CrossRefPubMedGoogle Scholar
  12. 12.
    Moe KE. Reproductive hormones, aging, and sleep. Semin Reprod Endocrinol. 1999;17(4):339–48.CrossRefPubMedGoogle Scholar
  13. 13.
    Roth T. Insomnia: definition, prevalence, etiology, and consequences. J Clin Sleep Med. 2007;3(5 Suppl):S7–10.PubMedPubMedCentralGoogle Scholar
  14. 14.
    NIH State-of-the-Science Conference Statement on manifestations and management of chronic insomnia in adults. NIH Consens State Sci Statements. 2005;22(2):1-30.Google Scholar
  15. 15.
    Mellinger GD, Balter MB, Uhlenhuth EH. Insomnia and its treatment. Prevalence and correlates. Arch Gen Psychiatry. 1985;42(3):225–32.CrossRefPubMedGoogle Scholar
  16. 16.
    Young T, Shahar E, Nieto FJ, et al. Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study. Arch Intern Med. 2002;162(8):893–900.CrossRefPubMedGoogle Scholar
  17. 17.
    Ancoli-Israel S, Kripke DF, Klauber MR, Mason WJ, Fell R, Kaplan O. Sleep-disordered breathing in community-dwelling elderly. Sleep. 1991;14(6):486–95.CrossRefPubMedPubMedCentralGoogle Scholar
  18. 18.
    Ancoli-Israel S, Kripke DF. Prevalent sleep problems in the aged. Biofeedback Self Regul. 1991;16(4):349–59.CrossRefPubMedGoogle Scholar
  19. 19.
    Woodward M. Insomnia in the elderly. Aust Fam Physician. 1999;28(7):653–8.PubMedGoogle Scholar
  20. 20.
    Rajput V, Bromley SM. Chronic insomnia: a practical review. Am Fam Physician. 1999;60(5):1431–8. discussion 1441-1432PubMedGoogle Scholar
  21. 21.
    Woodward M. Hypnosedatives in the elderly. CNS Drugs. 1999;11(4):263–79.CrossRefGoogle Scholar
  22. 22.
    Vgontzas AN, Kales A. Sleep and its disorders. Annu Rev Med. 1999;50:387–400.CrossRefPubMedGoogle Scholar
  23. 23.
    Ohayon MM. Nocturnal awakenings and comorbid disorders in the American general population. J Psychiatr Res. 2008;43(1):48–54.CrossRefPubMedGoogle Scholar
  24. 24.
    Rahman SA, Flynn-Evans EE, Aeschbach D, Brainard GC, Czeisler CA, Lockley SW. Diurnal spectral sensitivity of the acute alerting effects of light. Sleep. 2014;37(2):271–81.CrossRefPubMedPubMedCentralGoogle Scholar
  25. 25.
    Hattar S, Liao HW, Takao M, Berson DM, Yau KW. Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity. Science. 2002;295(5557):1065–70.CrossRefPubMedPubMedCentralGoogle Scholar
  26. 26.
    Hubbard J, Ruppert E, Gropp CM, Bourgin P. Non-circadian direct effects of light on sleep and alertness: lessons from transgenic mouse models. Sleep Med Rev. 2013;17(6):445–52.CrossRefPubMedGoogle Scholar
  27. 27.
    Patterson TL, Jeste DV. The potential impact of the baby-boom generation on substance abuse among elderly persons. Psychiatr Serv. 1999;50(9):1184–8.CrossRefPubMedGoogle Scholar
  28. 28.
    Neubauer DN. Sleep problems in the elderly. Am Fam Physician. 1999;59(9):2551–8, 2559-2560PubMedGoogle Scholar
  29. 29.
    Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14(6):540–5.CrossRefPubMedGoogle Scholar
  30. 30.
    Ohayon MM, Roth T. Prevalence of restless legs syndrome and periodic limb movement disorder in the general population. J Psychosom Res. 2002;53(1):547–54.CrossRefPubMedGoogle Scholar
  31. 31.
    Kushida CA, Littner MR, Morgenthaler T, et al. Practice parameters for the indications for polysomnography and related procedures: an update for 2005. Sleep. 2005;28(4):499–521.CrossRefPubMedGoogle Scholar
  32. 32.
    Milligan SA, Chesson AL. Restless legs syndrome in the older adult: diagnosis and management. Drugs Aging. 2002;19(10):741–51.CrossRefPubMedGoogle Scholar
  33. 33.
    Pilowsky I, Crettenden I, Townley M. Sleep disturbance in pain clinic patients. Pain. 1985;23(1):27–33.CrossRefPubMedGoogle Scholar
  34. 34.
    Wyse JM, Chen YI, Sahai AV. Celiac plexus neurolysis in the management of unresectable pancreatic cancer: when and how? World J Gastroenterol. 2014;20(9):2186–92.CrossRefPubMedPubMedCentralGoogle Scholar
  35. 35.
    Habermehl D, Brecht IC, Debus J, Combs SE. Palliative radiation therapy in patients with metastasized pancreatic cancer - description of a rare patient group. Eur J Med Res. 2014;19:24.CrossRefPubMedPubMedCentralGoogle Scholar
  36. 36.
    Cooke JR, Ancoli-Israel S. Normal and abnormal sleep in the elderly. Handb Clin Neurol. 2011;98:653–65.CrossRefPubMedPubMedCentralGoogle Scholar
  37. 37.
    Stepnowsky CJ, Ancoli-Israel S. Sleep and its disorders in seniors. Sleep Med Clin. 2008;3(2):281–93.CrossRefPubMedPubMedCentralGoogle Scholar
  38. 38.
    Postuma RB, Gagnon JF, Vendette M, Fantini ML, Massicotte-Marquez J, Montplaisir J. Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder. Neurology. 2009;72(15):1296–300.CrossRefPubMedPubMedCentralGoogle Scholar
  39. 39.
    Postuma RB, Gagnon JF, Montplaisir J. Rapid eye movement sleep behavior disorder as a biomarker for neurodegeneration: the past 10 years. Sleep Med. 2013;14(8):763–7.CrossRefPubMedGoogle Scholar
  40. 40.
    Iranzo A, Molinuevo JL, Santamaría J, et al. Rapid-eye-movement sleep behaviour disorder as an early marker for a neurodegenerative disorder: a descriptive study. Lancet Neurol. 2006;5(7):572–7.CrossRefPubMedGoogle Scholar
  41. 41.
    Drogos LL, Gill SJ, Tyndall AV, et al. Evidence of association between sleep quality and APOE ε4 in healthy older adults: a pilot study. Neurology. 2016;87(17):1836–42.CrossRefPubMedPubMedCentralGoogle Scholar
  42. 42.
    Gottlieb DJ, DeStefano AL, Foley DJ, et al. APOE epsilon4 is associated with obstructive sleep apnea/hypopnea: the Sleep Heart Health Study. Neurology. 2004;63(4):664–8.CrossRefPubMedGoogle Scholar
  43. 43.
    Grace JB, Walker MP, McKeith IG. A comparison of sleep profiles in patients with dementia with lewy bodies and Alzheimer's disease. Int J Geriatr Psychiatry. 2000;15(11):1028–33.CrossRefPubMedGoogle Scholar
  44. 44.
    Bliwise DL, Mercaldo ND, Avidan AY, Boeve BF, Greer SA, Kukull WA. Sleep disturbance in dementia with Lewy bodies and Alzheimer's disease: a multicenter analysis. Dement Geriatr Cogn Disord. 2011;31(3):239–46.CrossRefPubMedPubMedCentralGoogle Scholar
  45. 45.
    Weldemichael DA, Grossberg GT. Circadian rhythm disturbances in patients with Alzheimer's disease: a review. Int J Alzheimers Dis. 2010;2010.Google Scholar
  46. 46.
    Pollak CP, Perlick D. Sleep problems and institutionalization of the elderly. J Geriatr Psychiatry Neurol. 1991;4(4):204–10.PubMedGoogle Scholar
  47. 47.
    Gibson RH, Gander PH, Jones LM. Understanding the sleep problems of people with dementia and their family caregivers. Dementia. 2014;13(3):350–65.CrossRefPubMedGoogle Scholar
  48. 48.
    Lim MM, Gerstner JR, Holtzman DM. The sleep-wake cycle and Alzheimer's disease: what do we know? Neurodegener Dis Manag. 2014;4(5):351–62.CrossRefPubMedPubMedCentralGoogle Scholar
  49. 49.
    McCurry SM, Logsdon RG, Teri L, et al. Characteristics of sleep disturbance in community-dwelling Alzheimer's disease patients. J Geriatr Psychiatry Neurol. 1999;12(2):53–9.CrossRefPubMedGoogle Scholar
  50. 50.
    Bloom HG, Ahmed I, Alessi CA, et al. Evidence-based recommendations for the assessment and management of sleep disorders in older persons. J Am Geriatr Soc. 2009;57(5):761–89.CrossRefPubMedPubMedCentralGoogle Scholar
  51. 51.
    Dauvilliers Y. Insomnia in patients with neurodegenerative conditions. Sleep Med. 2007;8(Suppl 4):S27–34.CrossRefPubMedGoogle Scholar
  52. 52.
    Deschenes CL, McCurry SM. Current treatments for sleep disturbances in individuals with dementia. Curr Psychiatry Rep. 2009;11(1):20–6.CrossRefPubMedPubMedCentralGoogle Scholar
  53. 53.
    Khachiyants N, Trinkle D, Son SJ, Kim KY. Sundown syndrome in persons with dementia: an update. Psychiatry Investig. 2011;8(4):275–87.CrossRefPubMedPubMedCentralGoogle Scholar
  54. 54.
    Bedrosian TA, Nelson RJ. Sundowning syndrome in aging and dementia: research in mouse models. Exp Neurol. 2013;243:67–73.CrossRefPubMedGoogle Scholar
  55. 55.
    Schneider JA, Arvanitakis Z, Yu L, Boyle PA, Leurgans SE, Bennett DA. Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodies. Brain. 2012;135(Pt 10):3005–14.CrossRefPubMedPubMedCentralGoogle Scholar
  56. 56.
    Donaghy PC, McKeith IG. The clinical characteristics of dementia with Lewy bodies and a consideration of prodromal diagnosis. Alzheimers Res Ther. 2014;6(4):46.CrossRefPubMedPubMedCentralGoogle Scholar
  57. 57.
    Zupancic M, Mahajan A, Handa K. Dementia with lewy bodies: diagnosis and management for primary care providers. Prim Care Companion CNS Disord 2011;13(5).Google Scholar
  58. 58.
    Gooneratne NS, Vitiello MV. Sleep in older adults: normative changes, sleep disorders, and treatment options. Clin Geriatr Med. 2014;30(3):591–627.CrossRefPubMedPubMedCentralGoogle Scholar
  59. 59.
    Sack RL, Auckley D, Auger RR, et al. Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, and irregular sleep-wake rhythm. An American Academy of Sleep Medicine review. Sleep. 2007;30(11):1484–501.CrossRefPubMedPubMedCentralGoogle Scholar
  60. 60.
    Kantor ED, Rehm CD, Haas JS, Chan AT, Giovannucci EL. Trends in prescription drug use among adults in the United States from 1999-2012. JAMA. 2015;314(17):1818–31.CrossRefPubMedPubMedCentralGoogle Scholar
  61. 61.
    Tannenbaum C. Inappropriate benzodiazepine use in elderly patients and its reduction. J Psychiatry Neurosci. 2015;40(3):E27–8.CrossRefPubMedPubMedCentralGoogle Scholar
  62. 62.
    Madhusoodanan S, Bogunovic OJ. Safety of benzodiazepines in the geriatric population. Expert Opin Drug Saf. 2004;3(5):485–93.CrossRefPubMedGoogle Scholar
  63. 63.
    Mojtabai R, Olfson M. National trends in psychotropic medication polypharmacy in office-based psychiatry. Arch Gen Psychiatry. 2010;67(1):26–36.CrossRefPubMedGoogle Scholar
  64. 64.
    Panel AGSBCUE. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2012;60(4):616–31.CrossRefGoogle Scholar
  65. 65.
    Defrancesco M, Marksteiner J, Fleischhacker WW, Blasko I. Use of benzodiazepines in Alzheimer's disease: a systematic review of literature. Int J Neuropsychopharmacol. 2015;18(10):pyv055.CrossRefPubMedPubMedCentralGoogle Scholar
  66. 66.
    Bakken MS, Engeland A, Engesæter LB, Ranhoff AH, Hunskaar S, Ruths S. Risk of hip fracture among older people using anxiolytic and hypnotic drugs: a nationwide prospective cohort study. Eur J Clin Pharmacol. 2014;70(7):873–80.CrossRefPubMedPubMedCentralGoogle Scholar
  67. 67.
    de Jong MR, Van der Elst M, Hartholt KA. Drug-related falls in older patients: implicated drugs, consequences, and possible prevention strategies. Ther Adv Drug Saf. 2013;4(4):147–54.CrossRefPubMedPubMedCentralGoogle Scholar
  68. 68.
    Tinetti ME. Clinical practice. Preventing falls in elderly persons. N Engl J Med. 2003;348(1):42–9.CrossRefPubMedGoogle Scholar
  69. 69.
    Wagner J, Wagner ML. Non-benzodiazepines for the treatment of insomnia. Sleep Med Rev. 2000;4(6):551–81.CrossRefPubMedGoogle Scholar
  70. 70.
    Doty RL, Treem J, Tourbier I, Mirza N. A double-blind study of the influences of eszopiclone on dysgeusia and taste function. Pharmacol Biochem Behav. 2009;94(2):312–8.CrossRefPubMedGoogle Scholar
  71. 71.
    Brzezinski A, Vangel MG, Wurtman RJ, et al. Effects of exogenous melatonin on sleep: a meta-analysis. Sleep Med Rev. 2005;9(1):41–50.CrossRefPubMedGoogle Scholar
  72. 72.
    Wurtman RJ, Zhdanova I. Improvement of sleep quality by melatonin. Lancet. 1995;346(8988):1491.CrossRefPubMedGoogle Scholar
  73. 73.
    Serfaty M, Kennell-Webb S, Warner J, Blizard R, Raven P. Double blind randomised placebo controlled trial of low dose melatonin for sleep disorders in dementia. Int J Geriatr Psychiatry. 2002;17(12):1120–7.CrossRefPubMedGoogle Scholar
  74. 74.
    Singer C, Tractenberg RE, Kaye J, et al. A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer's disease. Sleep. 2003;26(7):893–901.CrossRefPubMedPubMedCentralGoogle Scholar
  75. 75.
    Roth T, Seiden D, Wang-Weigand S, Zhang J. A 2-night, 3-period, crossover study of ramelteon's efficacy and safety in older adults with chronic insomnia. Curr Med Res Opin. 2007;23(5):1005–14.CrossRefPubMedGoogle Scholar
  76. 76.
    Roth T, Seiden D, Sainati S, Wang-Weigand S, Zhang J, Zee P. Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia. Sleep Med. 2006;7(4):312–8.CrossRefPubMedGoogle Scholar
  77. 77.
    Mini LJ, Wang-Weigand S, Zhang J. Self-reported efficacy and tolerability of ramelteon 8 mg in older adults experiencing severe sleep-onset difficulty. Am J Geriatr Pharmacother. 2007;5(3):177–84.CrossRefPubMedGoogle Scholar
  78. 78.
    Johnson MW, Suess PE, Griffiths RR. Ramelteon: a novel hypnotic lacking abuse liability and sedative adverse effects. Arch Gen Psychiatry. 2006;63(10):1149–57.CrossRefPubMedGoogle Scholar
  79. 79.
    Mendelson WB. A review of the evidence for the efficacy and safety of trazodone in insomnia. J Clin Psychiatry. 2005;66(4):469–76.CrossRefPubMedGoogle Scholar
  80. 80.
    Bayer AJ, Pathy MS, Ankier SI. Pharmacokinetic and pharmacodynamic characteristics of trazodone in the elderly. Br J Clin Pharmacol. 1983;16(4):371–6.CrossRefPubMedPubMedCentralGoogle Scholar
  81. 81.
    Thase ME. Antidepressant treatment of the depressed patient with insomnia. J Clin Psychiatry. 1999;60(Suppl 17):28–31. discussion 46-28PubMedGoogle Scholar
  82. 82.
    Raskin DE. Trazodone and priapism. Am J Psychiatry. 1985;142(1):142–3.PubMedGoogle Scholar
  83. 83.
    Thase ME, Nierenberg AA, Keller MB, Panagides J, Group RPS. Efficacy of mirtazapine for prevention of depressive relapse: a placebo-controlled double-blind trial of recently remitted high-risk patients. J Clin Psychiatry. 2001;62(10):782–8.CrossRefPubMedGoogle Scholar
  84. 84.
    de Boer T. The pharmacologic profile of mirtazapine. J Clin Psychiatry. 1996;57(Suppl 4):19–25.PubMedGoogle Scholar
  85. 85.
    Verhamme KM, Sturkenboom MC, Stricker BH, Bosch R. Drug-induced urinary retention: incidence, management and prevention. Drug Saf. 2008;31(5):373–88.CrossRefPubMedGoogle Scholar
  86. 86.
    Laimer M, Kramer-Reinstadler K, Rauchenzauner M, et al. Effect of mirtazapine treatment on body composition and metabolism. J Clin Psychiatry. 2006;67(3):421–4.CrossRefPubMedGoogle Scholar
  87. 87.
    Fava M. Weight gain and antidepressants. J Clin Psychiatry. 2000;61(Suppl 11):37–41.PubMedGoogle Scholar
  88. 88.
    Viramontes TS, Truong H, Linnebur SA. Antidepressant-induced hyponatremia in older adults. Consult Pharm. 2016;31(3):139–50.CrossRefPubMedGoogle Scholar
  89. 89.
    Tripathi P, Tomar LR, Goyal P, Singh P. An unusual presentation of dose dependent SIADH secondary to mirtazapine therapy. Aust N Z J Psychiatry. 2015;49(11):1070–1.CrossRefPubMedGoogle Scholar
  90. 90.
    Remick RA. Anticholinergic side effects of tricyclic antidepressants and their management. Prog Neuro-Psychopharmacol Biol Psychiatry. 1988;12(2-3):225–31.CrossRefGoogle Scholar
  91. 91.
    Mandour RA. Antidepressants medications and the relative risk of suicide attempt. Toxicol Int. 2012;19(1):42–6.CrossRefPubMedPubMedCentralGoogle Scholar
  92. 92.
    Pearson NJ, Johnson LL, Nahin RL. Insomnia, trouble sleeping, and complementary and alternative medicine: analysis of the 2002 national health interview survey data. Arch Intern Med. 2006;166(16):1775–82.CrossRefPubMedGoogle Scholar
  93. 93.
    Meolie AL, Rosen C, Kristo D, et al. Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence. J Clin Sleep Med. 2005;1(2):173–87.PubMedGoogle Scholar
  94. 94.
    Tariq SH. Herbal therapies. Clin Geriatr Med. 2004;20(2):237–57.CrossRefPubMedGoogle Scholar
  95. 95.
    Liu QQ, Zhang J, Guo RJ, et al. Efficacy and safety of the Chaihuguizhiganjiang-suanzaoren granule on primary insomnia: study protocol for a randomised controlled trial. BMJ Open. 2016;6(2):e008459.CrossRefPubMedPubMedCentralGoogle Scholar
  96. 96.
    Watson NF, Badr MS, Belenky G, et al. Joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society on the recommended amount of sleep for a healthy adult: methodology and discussion. J Clin Sleep Med. 2015;11(8):931–52.PubMedPubMedCentralGoogle Scholar
  97. 97.
    Stepanski EJ, Wyatt JK. Use of sleep hygiene in the treatment of insomnia. Sleep Med Rev. 2003;7(3):215–25.CrossRefPubMedGoogle Scholar
  98. 98.
    Bootzin RR, Epstein D, Wood JM. Stimulus control instructions. In: Hauri P, editor. Case studies in insomnia. New York: Plenum Medical; 1991. p. 19–23.CrossRefGoogle Scholar
  99. 99.
    Alberg AJ, Shopland DR, Cummings KM. The 2014 Surgeon General's report: commemorating the 50th Anniversary of the 1964 Report of the Advisory Committee to the US Surgeon General and updating the evidence on the health consequences of cigarette smoking. Am J Epidemiol. 2014;179(4):403–12.CrossRefPubMedPubMedCentralGoogle Scholar
  100. 100.
    Ogeil RP, Phillips JG. Commonly used stimulants: sleep problems, dependence and psychological distress. Drug Alcohol Depend. 2015;153:145–51.CrossRefPubMedGoogle Scholar
  101. 101.
    Brower KJ, Hall JM. Effects of age and alcoholism on sleep: a controlled study. J Stud Alcohol. 2001;62(3):335–43.CrossRefPubMedPubMedCentralGoogle Scholar
  102. 102.
    Angarita GA, Emadi N, Hodges S, Morgan PT. Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review. Addict Sci Clin Pract. 2016;11(1):9.CrossRefPubMedPubMedCentralGoogle Scholar
  103. 103.
    Spielman AJ, Saskin P, Thorpy MJ. Treatment of chronic insomnia by restriction of time in bed. Sleep. 1987;10(1):45–56.PubMedGoogle Scholar
  104. 104.
    Harsora P, Kessmann J. Nonpharmacologic management of chronic insomnia. Am Fam Physician. 2009;79(2):125–30.PubMedGoogle Scholar
  105. 105.
    Smith MT, Perlis ML. Who is a candidate for cognitive-behavioral therapy for insomnia? Health Psychol. 2006;25(1):15–9.CrossRefPubMedGoogle Scholar
  106. 106.
    Edinger JD, Olsen MK, Stechuchak KM, et al. Cognitive behavioral therapy for patients with primary insomnia or insomnia associated predominantly with mixed psychiatric disorders: a randomized clinical trial. Sleep. 2009;32(4):499–510.CrossRefPubMedPubMedCentralGoogle Scholar
  107. 107.
    Jacobs GD, Pace-Schott EF, Stickgold R, Otto MW. Cognitive behavior therapy and pharmacotherapy for insomnia: a randomized controlled trial and direct comparison. Arch Intern Med. 2004;164(17):1888–96.CrossRefPubMedGoogle Scholar
  108. 108.
    Smith MT, Huang MI, Manber R. Cognitive behavior therapy for chronic insomnia occurring within the context of medical and psychiatric disorders. Clin Psychol Rev. 2005;25(5):559–92.CrossRefPubMedGoogle Scholar
  109. 109.
    Perlis ML. Cognitive behavioral treatment of insomnia: a session-by-session guide. New York, NY: Springer; 2005.Google Scholar
  110. 110.
    Shub D, Darvishi R, Kunik ME. Non-pharmacologic treatment of insomnia in persons with dementia. Geriatrics. 2009;64(2):22–6.PubMedGoogle Scholar
  111. 111.
    JQ W, Appleman ER, Salazar RD, Ong JC. Cognitive behavioral therapy for insomnia comorbid with psychiatric and medical conditions: a meta-analysis. JAMA Intern Med. 2015;175(9):1461–72.CrossRefGoogle Scholar

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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Washington Heights Community Services of the New York State Psychiatric Institute, Columbia University Medical CenterNew YorkUSA

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