Economic Burden of Clostridium difficile Infection in European Countries

  • Elena Reigadas Ramírez
  • Emilio Santiago Bouza
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1050)


Clostridium difficile infection (CDI) remains a considerable challenge to health care systems worldwide. Although CDI represents a significant burden on healthcare systems in Europe, few studies have attempted to estimate the consumption of resources associated with CDI in Europe. The reported extra costs attributable to CDI vary widely according to the definitions, design, and methodologies used, making comparisons difficult to perform. In this chapter, the economic burden of healthcare facility–associated CDI in Europe will be assessed, as will other less explored areas such as the economic burden of recurrent CDI, community-acquired CDI, pediatric CDI, and CDI in outbreaks.


C. difficile infection Economic costs Economic burden Length of stay Europe 


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© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Department of Clinical Microbiology and Infectious DiseasesHospital General Universitario Gregorio MarañónMadridSpain
  2. 2.Medicine Department, School of MedicineUniversidad Complutense de Madrid (UCM)MadridSpain
  3. 3.Instituto de Investigación Sanitaria Gregorio MarañónMadridSpain
  4. 4.CIBER de Enfermedades Respiratorias (CIBERES CB06/06/0058)MadridSpain

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