Abstract
Inflammatory Bowel Disease (IBD) is a group of chronic immune-mediated, polygenic disorders that relapse and remit, affecting predominantly adolescents and young adults. The pediatric population, however, accounts for 10–15% of cases, most often in those older than 10 years of age. Patients under the age of 20 account for 25% of newly diagnosed cases with IBD. IBD affects more than one in every 1000 individuals in Western countries and is becoming more common in the rest of the world. It arises when an inappropriate immune response of the intestine is mounted against the components of the bacterial flora occurring in genetically predisposed individuals [1]. The instability and reduction of microbiota biodiversity (dysbiosis) are currently the most studied etiopathogenic factors in Crohn’s disease [2].
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Buche, S., Delaporte, E. (2018). Neutrophilic Dermatoses in Digestive Disorders. In: Wallach, D., Vignon-Pennamen, MD., Valerio Marzano, A. (eds) Neutrophilic Dermatoses. Springer, Cham. https://doi.org/10.1007/978-3-319-72649-6_18
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DOI: https://doi.org/10.1007/978-3-319-72649-6_18
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